Why am I feeling great on medications for GERD and then nausea?

Prescriptions for GERD cause your stomach to stop producing acids which are required to digest your food. They can also cause some damage to the stomach lining. The most commonly reported side effects included headache, abdominal pain, nausea, and diarrhea. Other side effects of Prilosec (omprazole) for instance includes pains in the stomach, side, or abdomen, possibly radiating to the back, nausea. indigestion, vomiting, stomach pain, diarrhea or loose stools, heartburn, bloody or cloudy urine. chills, general feeling of discomfort or illness, loss of appetite, unusual bleeding or bruising, and others.
Long term, some of these remedies may cause problems with the stomach lining, which may cause the stomach from being able to digest B-12 which may lead to pernicious anemia.

You should ask your doctor about possibly treating your GERD with changes to your diet, or by changing the other prescription medications you are taking which may be causing the GERD.

In some cases it has been possible to identify the foods which are causing the GERD by keeping a food diary and this will help to identify the root of the problem by referring back to the foods eaten just prior to the GERD symptoms.

Look for a PPI with longer half life.

Thank you so much for the response and great advice!

Good luck

I too take a ppi for me esophagitis. But there’s a myth that all ppi’s are the same. This is not true at all. I’ve been on many. And have gottten so many different side effects from them. While they are amazing at eliminating the pain in my chest some have caused me severe nausea, fatigue headaches constipstion etc. maybe it’s time for a meds change. Also have you made changes in your diet? Not eating after 7 pm? It really does help a lot. Good luck. You’re not alone!!!😊😊😊😊😊

Thank you so much!

I just had a colonoscopy/endoscopy yesterday. I'm 82 so past the age for a routine but have had IBS-D for over forty years and it has gotten worse and I also have a dry cough, pains in my upper GI area and heartburn. Turns out I have a "perfect" colon but I have very inflammed upper GI. Distal Esophagitis, Gastritis without bleeding, Duodenitis, Of course she ordered Rx Omeprozole and Sucralfate. I had a bleeding ulcer over 30 years ago and that's what I was on. You would think in all these years they would have come up with something newer. I already have the IBS-D, and Omeprozole doesn't help. Besides diet modification what other things help? I am already gluten free and don't drink so I'm guessing cutting out citrus, onions, coffee and tea? My food world is getting smaller and smaller.

Depending on the cause of your esophagitis, I suppose surgery may be helpful. But a lot of us use diet and lifestyle changes instead of surgery and drugs. There is a lot of free info at https://jamiekoufman.com. There is also a FB group with a ton of recipes for eating a low-acid, whole food diet: https://www.facebook.com/groups/199013402360712. There are also free videos by Dr. Aviv. As mentioned previously, a food diary also would be helpful. A few lifestyle changes would be sleeping with your head elevated, wrap up eating at least three hours before bedtime and eating more frequent, smaller meals. I feel for you about your food world getting smaller. If you like to cook than the FB group will broaden your food choices for low acid, whole food meals. Good luck!