When is forteo prescribed and when is evenity prescribed?

mijas07,
I didn't have any side effects.
Within seconds of the injection the hormone pulls calcium from your bones, your digestive tract and back from your kidneys. You'll have about four hours of higher calcium levels.
Higher calcium levels dilate your blood vessels. More room in your blood vessels causes your blood pressure to drop and your heart to beat faster to keep the blood circulating at speed; It can cause a headache and/or nausea.
Salt and caffeine constrict your blood vessels. And extra fluids increase serum volume. I like a green olive and a glass of water before the injection. Tea or coffee might work even better, but not if you take the medication before sleep. If it did make you dizzy, you don't want to have to get up dizzy and half asleep.
If you inject in the morning just plan easy activities for the first few hours until you see how it affects you.
I was laughably cautious the first week, taking my blood pressure as fast as I could reset the cuff. I have low blood pressure usually 100/60, I'd lose 20 points on the systolic immediately, but I never felt anything.
Some do have allergic reactions to Forteo. But it is so easy to stop taking it. It leaves your system mostly in the first four hours.
It is a great drug to alert a patient to problems with their parathyroid glands or kidneys.
Mijas, it's good to use bone markers to make sure that Forteo is building bone. P1NP usually rises rapidly in the first two months. CTX will let you know if the effectiveness is lessening at a later point in time.
You might ask your physician to order CTX and P1NP before you start and two months in.
I hope Forteo will bless your bones. It's likely.

Thank you so so much for that detailed reply.
I've been feeling quite scared about it but yes I'll ask for those markers before and after.
I have low blood pressure anyway so the start of your post scared me a bit.
What I love about this drug is that you can stop if the effects are too severe and no harm done.
I really do hope that it works as well for me as it did for you.
I love tea/coffee and salt so if I can have those post-injection....well even better!! I'm doing it to keep my blood pressure up 🙂
Many thanks xx

Hi, Helenrose,
I keep reading about how important it is to continue Forteo for the full dose--two years. There may be some complicated thinking behind the decision for your use of only one year. I don't think you get the full advantage of Forteo until the second year, most especially in the hips.
The endocrinologist now plans to leave me on Forteo until my T score is -1, by which I think he means from now on. I didn't think we could ever get back to -1, but when I do, I'll ask for another year.
I hope your doctor agrees to your request.

From what I understand, the gains with Forteo are rapid and then drop off significantly after the first year or maybe even at the latter end of the first year for some. Since PTH can have a catabolic effect on bone density, this short burst of hormone is "trickery" that the body eventually figures out, thus diminishing the bone building effect of the initial use. In my case, I went from -3.2 to -2.8 the first year and then to -2.9 the second, so I actually slightly lost density the second year. I think bone markers are crucial, from baseline and every few months to make sure the drug is still working in your favor.

oh, Teb. I think you have later information than I have. https://pmc.ncbi.nlm.nih.gov/articles/PMC4947115/#:~:text=Summary%20In%20patients%20with%20osteoporosis,outcomes%20than%20shorter%20time%20periods.
Of course your own experience trumps anything written in these studies.
I would be interested in your bone markers throughout, if you have them handy and are willing.
I had a slow rise in bone markers in the first year and no real change in bmd, but a little change in fracture risk. The second year gave me real changes in P1NP plus changing my lowest reading from -3.3 to -2.6. If the bone markers are any measure this next dxa will show even more improvement.
The burst of hormone is a daily trick. The rise of P1NP instigates the rise of CTX which eventually exceeds the advantage of P1NP.
Were you able to get bone markers ordered every few months. The endocrinologist I see gave me a standing order for every three months. And I depend upon Jason Health for the rest. It is good to hear your results.

I took Forteo about 9-10 years ago. If I recall correctly, my doctor ordered one set of bone marker tests in the first few months to determine it was working and then a dexa at one year. Unfortunately, I wasn't as informed back then on the importance of bone markers so I did not request it on a regular basis. At the time, I was under the care of two endocrinologists who specialize in osteoporosis management and they just followed the drug manufacturer's recommendation with little thought as to personalization and optimization. Along those lines, one thing that makes me somewhat skeptical of the study cited (other than my personal experience of losing density the second year of treatment) is that it was sponsored/paid for by Ely Lily with all authors involved either employees, investors or consultants which gives rise to a slant towards recommendation of full compliance of a 2 year protocol. It does state that "a clinical trial in which patients are randomized to different durations of teriparatide treatment has not been performed"

Yes, and thanks. The only "study" I completely trust are the patient experience recorded here, like yours. And mine. So different. All of which makes us reminds us of (your point) about the need for "personalization and optimization," and bone markers.

I took Forteo about 9-10 years ago. If I recall correctly, my doctor ordered one set of bone marker tests in the first few months to determine it was working and then a dexa at one year. Unfortunately, I wasn't as informed back then on the importance of bone markers so I did not request it on a regular basis. At the time, I was under the care of two endocrinologists who specialize in osteoporosis management and they just followed the drug manufacturer's recommendation with little thought as to personalization and optimization. Along those lines, one thing that makes me somewhat skeptical of the study cited (other than my personal experience of losing density the second year of treatment) is that it was sponsored/paid for by Ely Lily with all authors involved either employees, investors or consultants which gives rise to a slant towards recommendation of full compliance of a 2 year protocol. It does state that "a clinical trial in which patients are randomized to different durations of teriparatide treatment has not been performed"

hi Teb. You took Forteo 9-10 Years ago? May I ask what your journey has been since then? I took the full course in 2016, followed by one shot of Prolia and then 6 years on Raloxifene . Now on Forteo generic brand Teva-Teriparatide. Purposal is to follow with Evenity then Prolia. I'm not sure. Thinking Roloxafin the kinder of those options.