When is forteo prescribed and when is evenity prescribed?

Posted by helenrose @helenrose, 2 days ago

I have had 2 suggestions for my next med for osteoporosis. I had 2 reclast infusions which helped maintain and build back some bone. At moment no bone loss happening. One of my doctor's who is an expert on bone health is suggesting evenity. My endocrinologist is suggesting forteo. I took forteo about 25 years ago and it helped build bone back. However I did not take anything afterwards that would hold it. Also had no side effects. In terms of evenity the other doctor suggested it as she said it helped build bone back more quickly I believe. I am 79 years old. Not sure which to do? Thanks.

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

helenrose,
Evenity is a newer drug, more heavily advertised, with a black box for cardiac issues. The bone expert is right that it adds bone more quickly. The bone it adds is surface bone somewhat like a scaffold. Evenity doesn't remodel bone.
Forteo and Tymlos are the two medications that remodel bone. They remove bone that is fissured or damaged and replace it with fresh bone. Neither of these medications have a black box warning attached for health.
And any of these drug can cause miserable side effects. Forteo would be the safest for you in regard to side effects, because you already took it 25 years ago.
Doctors prescribe because of what they've seen and what they haven't see; heard and haven't heard. Right now they are hearing a lot about Evenity--the newest tool in the box. My own doctor has just been offered a speaking engagement with Amgen, and will, no doubt, be prescribing it more often.
Cost and ease of use can also factor in as Medicare pays for Evenity under part B.
I'm on my third year of Forteo. It has been a wonderful drug for me.
Bless your choice.

REPLY
@gently

helenrose,
Evenity is a newer drug, more heavily advertised, with a black box for cardiac issues. The bone expert is right that it adds bone more quickly. The bone it adds is surface bone somewhat like a scaffold. Evenity doesn't remodel bone.
Forteo and Tymlos are the two medications that remodel bone. They remove bone that is fissured or damaged and replace it with fresh bone. Neither of these medications have a black box warning attached for health.
And any of these drug can cause miserable side effects. Forteo would be the safest for you in regard to side effects, because you already took it 25 years ago.
Doctors prescribe because of what they've seen and what they haven't see; heard and haven't heard. Right now they are hearing a lot about Evenity--the newest tool in the box. My own doctor has just been offered a speaking engagement with Amgen, and will, no doubt, be prescribing it more often.
Cost and ease of use can also factor in as Medicare pays for Evenity under part B.
I'm on my third year of Forteo. It has been a wonderful drug for me.
Bless your choice.

Jump to this post

@gently: Big Thank You for your thoughts and explanations of Evenity and Forteo!!! This info is so helpful to my research on Osteoporosis Drugs… just in case my recent DEXA scan shows Osteoporosis progression. Last appt Dr talked about Prolia and from what I have learned from this blog is to Stay Away from Prolia. Thank you so much for sharing your expertise!

REPLY
@gently

helenrose,
Evenity is a newer drug, more heavily advertised, with a black box for cardiac issues. The bone expert is right that it adds bone more quickly. The bone it adds is surface bone somewhat like a scaffold. Evenity doesn't remodel bone.
Forteo and Tymlos are the two medications that remodel bone. They remove bone that is fissured or damaged and replace it with fresh bone. Neither of these medications have a black box warning attached for health.
And any of these drug can cause miserable side effects. Forteo would be the safest for you in regard to side effects, because you already took it 25 years ago.
Doctors prescribe because of what they've seen and what they haven't see; heard and haven't heard. Right now they are hearing a lot about Evenity--the newest tool in the box. My own doctor has just been offered a speaking engagement with Amgen, and will, no doubt, be prescribing it more often.
Cost and ease of use can also factor in as Medicare pays for Evenity under part B.
I'm on my third year of Forteo. It has been a wonderful drug for me.
Bless your choice.

Jump to this post

Thanks so much. My doc had said I would be on forteo for a year. I could ask her about longer. Is this third year your last year on forteo?

REPLY
@dbamos1945

@gently: Big Thank You for your thoughts and explanations of Evenity and Forteo!!! This info is so helpful to my research on Osteoporosis Drugs… just in case my recent DEXA scan shows Osteoporosis progression. Last appt Dr talked about Prolia and from what I have learned from this blog is to Stay Away from Prolia. Thank you so much for sharing your expertise!

Jump to this post

Yes I had a friend who was a PT. She went on prolia and had a spontaneous fracture of her hip. She is positive it was the prolia. Also another doctor Lonnie Simpson, who is an expert on bone stuff here on the West Coast does not recommend prolia. Not sure why. She likes forteo and evenity I believe.

REPLY
@helenrose

Thanks so much. My doc had said I would be on forteo for a year. I could ask her about longer. Is this third year your last year on forteo?

Jump to this post

Hi, Helenrose,
I keep reading about how important it is to continue Forteo for the full dose--two years. There may be some complicated thinking behind the decision for your use of only one year. I don't think you get the full advantage of Forteo until the second year, most especially in the hips.
The endocrinologist now plans to leave me on Forteo until my T score is -1, by which I think he means from now on. I didn't think we could ever get back to -1, but when I do, I'll ask for another year.
I hope your doctor agrees to your request.

REPLY
@helenrose

Yes I had a friend who was a PT. She went on prolia and had a spontaneous fracture of her hip. She is positive it was the prolia. Also another doctor Lonnie Simpson, who is an expert on bone stuff here on the West Coast does not recommend prolia. Not sure why. She likes forteo and evenity I believe.

Jump to this post

Did you have any side effects at all from Forteo? Thanks.

REPLY
@gently

helenrose,
Evenity is a newer drug, more heavily advertised, with a black box for cardiac issues. The bone expert is right that it adds bone more quickly. The bone it adds is surface bone somewhat like a scaffold. Evenity doesn't remodel bone.
Forteo and Tymlos are the two medications that remodel bone. They remove bone that is fissured or damaged and replace it with fresh bone. Neither of these medications have a black box warning attached for health.
And any of these drug can cause miserable side effects. Forteo would be the safest for you in regard to side effects, because you already took it 25 years ago.
Doctors prescribe because of what they've seen and what they haven't see; heard and haven't heard. Right now they are hearing a lot about Evenity--the newest tool in the box. My own doctor has just been offered a speaking engagement with Amgen, and will, no doubt, be prescribing it more often.
Cost and ease of use can also factor in as Medicare pays for Evenity under part B.
I'm on my third year of Forteo. It has been a wonderful drug for me.
Bless your choice.

Jump to this post

It sounds like Forteo works well for you. I'm due to start in about a months time after some blood tests. I'm scared of the side effects - did you have any when you started? Thanks for giving me hope that it might work for me too 🙂

REPLY

I have been on Evenity since last December. In the last month have developed pain in my lower sacrum and wondering if anyone else has the same side effect. Just had my 5th shots last week. Also the cost of my co-payment is over $450 a month after deductions with Blue Cross Mn Advantage! Since this is a new drug there is no help until I hit my deductible.?

REPLY
@mijas07

It sounds like Forteo works well for you. I'm due to start in about a months time after some blood tests. I'm scared of the side effects - did you have any when you started? Thanks for giving me hope that it might work for me too 🙂

Jump to this post

mijas07,
I didn't have any side effects.
Within seconds of the injection the hormone pulls calcium from your bones, your digestive tract and back from your kidneys. You'll have about four hours of higher calcium levels.
Higher calcium levels dilate your blood vessels. More room in your blood vessels causes your blood pressure to drop and your heart to beat faster to keep the blood circulating at speed; It can cause a headache and/or nausea.
Salt and caffeine constrict your blood vessels. And extra fluids increase serum volume. I like a green olive and a glass of water before the injection. Tea or coffee might work even better, but not if you take the medication before sleep. If it did make you dizzy, you don't want to have to get up dizzy and half asleep.
If you inject in the morning just plan easy activities for the first few hours until you see how it affects you.
I was laughably cautious the first week, taking my blood pressure as fast as I could reset the cuff. I have low blood pressure usually 100/60, I'd lose 20 points on the systolic immediately, but I never felt anything.
Some do have allergic reactions to Forteo. But it is so easy to stop taking it. It leaves your system mostly in the first four hours.
It is a great drug to alert a patient to problems with their parathyroid glands or kidneys.
Mijas, it's good to use bone markers to make sure that Forteo is building bone. P1NP usually rises rapidly in the first two months. CTX will let you know if the effectiveness is lessening at a later point in time.
You might ask your physician to order CTX and P1NP before you start and two months in.
I hope Forteo will bless your bones. It's likely.

REPLY
Please sign in or register to post a reply.