What was your highest PSA and still have a clear PET/CT scan?

My Advanced Prostate Cancer (APC) 8 Phases Theory: Phase #1 Somethings amiss. Phase #2 What’s BPH? Phase #3 Diagnosis. Phase #4 What’s an Oncologist? Phase #5 The “You can never be Cured, only Treated Talk.” Phase #6 Intervention Treatment (stop the pain and control the spread). Phase #7 Quality of Life Treatment Plan. Phase #8 Doubling while Looking for Miracles.

I’m in the doubling phase. Paradox, I am living the best version of myself. Why? Living an Advanced Prostate Cancer (APC) phase helps you live with a deep intimacy and gratitude of everyday life.

Thank you for your reply.
I am trying to live the best version of myself as well.
And yes, Advanced aggressive Prostate Cancer does change ones perspective on many things in life.

I went in for another PSA test today before my tel-med with my oncologist this Thursday. It showed another steep increase in six weeks it went up 4.09 points. From 6.67 to 10.58.
My PSA results this year;
01/05/2024 PSA 0.08
03/11/2024 PSA 1.02
06/10/2024 PSA 6.67
07/22/2024 PSA 10.58
PET/CT scan on 07/11/2024 results "There is no abnormal PSMA uptake to indicate recurrence or metastatic disease anywhere despite the rising PSA."
I am very confused and getting concerned about whats next...

That is confusing. Let us know what your doctors tell you and an explanation of the scan results. Thank you. Blessings.

Confused PSA up to 3104 Finished 6 injections of Radium 223 Whats next Bone cancer slowed yet new in 9th rib and T 5

Help On Zolodex and Xgeva Xtandi failed last year after 11 months

Re do the PET SCAN. It’s not infallible

Yes, I think that will be next.

I had a similar experience to yours when I recurred in 2018. Rapid doubling time but couldn’t find on scans. PSA got up to 5 without finding anything. The opinion was that the cancer was small bits, scattered around. Each bit too small to show significant uptake. I did PSMA and choline PET scans.

Not all prostate cancers are PSMA avid. There other PET scans that do not depend on PSMA.

My most recent PSA was 10.58 up about four points in six weeks. Recent PET/CT scan was clear.
I had a virtual visit with my Oncologist yesterday. He said that if the scan had shown metastases then they would have a clear idea of where the cancer had spread and that they would be able to do a more targeted approach to treatment. But that was not the case.
So now I will be resuming Orgovyx and this time I will also be taking Xtandi instead of Erleada.
When I was on Orgovyx and Erleada last year my PSA dropped from 13.46 to 0.15 in one month. After three months PSA was < 0.01. PSA It remained undetectable for about three months but started to climb once I stopped taking the drugs. It continued to climb for 7 months to where it is now 10.58.
The side effects I experienced with the Orgovyx and Erleada combo were tolerable but I am not looking forward to living with them again. The side effects were; hot flashes, loss of muscle strength, loss of bone density, loss of body hair, loss of libido, increased breast size, and the worst one for me was joint pain.
I expected the treatments would resume and that the side effects would be similar to last years. I live in a 140 year old general store building with the main living space on the second floor. The side effects of the drugs last year made it painful to navigate the 21 steps up to my apartment. So over the last few months I have been renovating a small apartment on the first floor of my building, just in case. I am very happy that I decided to do the renovation, I may be living down there sooner than later.