What happens when you stop taking anastrozole?

Posted by kamra @kamra, May 7, 2023

I've been taking anastrozole for six months to shrink tumors in preparation for surgery. I stopped taking it about a week and a half ago as the doctor ordered since my surgery is coming up. I've felt weird and not very well since stopping. I've been tired, kind of dizzy, and just not feeling myself. Anyone have experience with side effects when stopping Anastrozole? Thank you. I go back on it after surgery.

Interested in more discussions like this? Go to the Breast Cancer Support Group.


No problems for about 4 years. I had a heart incident. I cant blame Exemestane because the cardiologist said i either passed a clot or had an arterial spasm. He asked if Exemestane was a pro thrombotic. I had a friend research it and theres a 1% effect with certain people.
I just wanted you to know, not to spread fear.
Personally, I would give it a try. See how you do for 3 months.
If you have any type of side effects, stop it n discuss with your doctor.
Take a look at DIM.
I’ve heard people say its a good alternative.
I actually may consider it myself.

Jump to this post

What is DIM ?


I would think about getting another Oncologist! They are trying different medications for me to see if they can lessen the side effects.

Jump to this post

I have had 3 oncologists, to date: one in Illinois (bad); one in Iowa City (vote is out) and one in Texas (good). I quit going to the Illinois one after his complete indifference to my condition became clearer and clearer. The "minions" also made it clear that their only concern was keeping you coming back for that scheduled visit.

When I had my Oct. 3, 2022, first post-operative mammogram I was in a wheelchair, thanks to the side effects of Anastrozole, coupled with my fragile left knee and old age, The symptoms were consistent with a meniscus tear, and I gambled that it would get better if I stayed off it for a period of months (it did). However, I anticipated a bit of "owning up" to the fact that drugs like Anastrozole (any of the A.I. drugs) will inflame arthritic joints and damaged joints. No such luck. The Illinois oncologist simply chalked it up to old age (77 at the time) and left the room with no discussion at all of alternatives to taking a pill or pills (A.I.) that were guaranteed to give me excruciating joint pain. He acted like he could have cared less and didn't want to be bothered.
As I left the last appointment with "the minions" they talked about my fast-declining bone density, as measured on a recent test, and urged me to "make an appointment on your way out." I explained---for the umpteenth time---that I could not make an appointment until I knew when we would be back in town. I told them I would call when we returned to the Illinois Quad Cities. That was in October of 2022.
Imagine my surprise to be sitting on my couch in Austin, Texas in April of 2023 and to receive a phone call telling me that I had an appointment on April 19th. My response was, "No, I don't." It seems that the minions had simply made an appointment for me without any input or "okay" from me. This seriously rankled me, and I quit going to the bad Illinois oncologist from that point on. I had had a second opinion from an oncologist in Iowa City at the University of Iowa Hospitals and Clinics, and I now drive an hour and a half to doctor there, if I need to doctor at all. I prefer to be supervised by my Texas oncologist, who seems on top of things and listens to what I tell him. He recently sent me for a CT scan with contrast when my LFT (liver function test) scores spiked. I now have a Texas driver's license and will vote in Texas in November. I do not ever want to have to have anything to do with the Illinois oncologist whose attitude is seriously narcissistic and godlike. Getting up and walking out while proclaiming, "I won't order that for you. You'll have to get someone else" is pretty bad when the "something" was a test suggested by the attending surgeon, primarily because the oncologist hadn't ordered the oncotype he should have ordered at the beginning of the entire saga. (With the oncotype, I would not have needed the ki67, which also gauges the aggressiveness of the tumor.) I am still in search of tests that will help a breast cancer survivor to know if her disease has recurred. I haven't had much luck having any of these physicians order up MRIs for me, and yet the mammograms are said to miss many instances of cancer if the patient (i.e., me) has a history of dense breast tissue.


I had to stop take ng Anastrazole as I had another surgery scheduled. Had the surgery an eventually resumed takin Anastrazole. Don’t recall any reactions to stopping for the short term. In the long term the risk of NOT taking Anastrazole would be increased of metastasis if breast cancer.

Please sign in or register to post a reply.