What happens after Tymlos?

He claims it is the best drug on the market to hold the gains I made with Tymlos. He is a Rheumatologist who was highly recommended. Good idea about the 2nd opinion, tho.

@gravity3 Hi there. My cardiologist is very confident with HRT replacement after finishing up my Tymlos. My rheumatologist wants me to begin Reclast infusion, so I’m researching and weighing my risks and benefits from both. I know I need HRT for my girlie parts for sure because I have suffered for years with vaginal atrophy so that will be a plus. But I would like the least amount of medication to maintain the gains I’ve had with Tymlos. I will have another Dexa scan next month and will see if the additional months on this med made a difference. I had a Dexa in Nov after being on Tymlos for 18 months but my doc approved for me to continue to the 24th month. Hoping there will be more gains.
I know it will take a couple of months for me to notice a difference with the HRT so I’m hoping I will feel the difference in my sleep, energy, sex, moods, etc. My doc says I will. Have a great weekend!

@dooshie just to be clear, while my Reclast dose will be lower, it will also be more frequent. Much depends on how I react (my first infusion is this week) and the doctor leaves the dose and timing up to me, as long as it meets his guidelines for effectiveness. He gives me parameters and I appreciate both his guidance and his caution. I have afib and kidney disease so the suggestion of lower dose came from the doctor.

How did your reclast infusion go? I hope it went well!

Low fever for 5 days, one episode of muscle spasm. Doing fine thanks!

Good evening @alknapp and welcome to Connect. You have started a new discussion about what might be the best follow-up to Tymlos. I am glad to see that @windyshores has jumped right in to help you. And now I will try to help you by relaying my positive post-Tymlos experience.

After two successful years with Tymlos, my endocrinologist told me that the only option for me upon completion of Tymlos was Prolia. I didn't know enough at the time to dig in and do my own research. So I had twoProlia injections in the first year. After the first injection, I began to struggle with jaw pain. I kept a calendar that tracked the pain level and the number of days it lasted. At the same time, I started doing some research right here on Connect. Fortunately, my PCP recognized my struggle with Prolia and helped me secure a consultation with Dr. Wermers, an Endocrinologist at the Mayo Clinic.

The solution was to begin a weekly tablet of Alendronate (Fosamax) on the day that I was scheduled for my next injection of Prolia. This decision reduced the half-life amount of medication that was in my body. Some of us just don't have the ability to handle injections that last 6 months.

Suffice it to say, I will have completed 2 years of Alendronate this summer without any side effects. Then it will be time for a Dexa scan and I will know how well this medication maintained the bone that Tymlos built for me as well as the rest of the bone in my body.

Good luck with your decision. Please know that I am here for you.

May you be safe, protected, and free from inner and outer harm.
Chris

Chris, I just started taking tymlos (10 days) and my heart is still racing. Per the tymlos site, the side effects will stop after the body gets used to it. I'm hoping you can tell me if this did happen to you,do you remember how long it took for your body to get used to tymlos?
Thank you

Chris, I just started taking tymlos (10 days) and my heart is still racing. Per the tymlos site, the side effects will stop after the body gets used to it. I'm hoping you can tell me if this did happen to you,do you remember how long it took for your body to get used to tymlos?
Thank you

@zygote maybe try going down to a half dose ( 4 clicks of the pen) and then work up. I even went down to 1/4 dose (2 clicks) and worked up to 7 clicks. I was never really able to tolerate the full 8 clicks but had excellent gains. Ramping up from a lower dose lets the body get used to it without so much suffering !

This means using the pen for more than 30 days, potentially, so keep it in the fridge...

Good evening, Zygote. I just reviewed your comment about Tymlos. I was actually a bit surprised by your comment about the side-to-side effects. This did not appear when I began my association with Tymlos three years ago. I may have had some minimal discomfort, but no pain.

I had started on Boniva and that was the wrong choice. After two months of tracking my levels of discomfort, my PCP and Endocrinologist suggested Tymlos. That turned out to be the right choice for me.

Good luck and good choices. Let me know how it works now.
Chris