1. < Prostate Cancer

Upcoming SBRT

Posted by gshep @gshep, 2 days ago

Upcoming SBRT. For those who have had SBRT and experienced, can you offer any advice for diet during this treatment period ? Can you discuss any side effects as the result of SBRT, during treatment and after treatment ? I’m hoping I made the right choice in choosing SBRT. Thank you

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

thmssllvn | @thmssllvn | 1 day ago

It is my understanding that ADT
stops the clock as it were for
progression. It also sensitizes the prostate tissue to radiotherapy
by ‘67’% I read that the 2nd gen ADT Nubeca (dorsolimab) sp? further sensitizes to 100%. However the approval of that 2nd drug may require meeting certain
criteria PSA>20?, etc.

REPLY
1 reply
jeffMar | @jeffmarc | 1 day ago
In reply to @thmssllvn "It is my understanding that ADT stops the clock as it were for progression. It also..." + (show)
@thmssllvn

It is my understanding that ADT
stops the clock as it were for
progression. It also sensitizes the prostate tissue to radiotherapy
by ‘67’% I read that the 2nd gen ADT Nubeca (dorsolimab) sp? further sensitizes to 100%. However the approval of that 2nd drug may require meeting certain
criteria PSA>20?, etc.

Jump to this post

Yes, ADT does stop the Metastasis from growing And can also shrink them. It doesn’t work forever, however. Most people on it for a long time become castrate resistant and have to move on to other drugs or other treatments.

REPLY
1 reply
thmssllvn | @thmssllvn | 1 day ago
In reply to @jeffmarc "Yes, ADT does stop the Metastasis from growing And can also shrink them. It doesn’t work..." + (show)
@jeffmarc

Yes, ADT does stop the Metastasis from growing And can also shrink them. It doesn’t work forever, however. Most people on it for a long time become castrate resistant and have to move on to other drugs or other treatments.

Jump to this post

Dr. Scholz also commented that 1st and 2nd generation ADTs work better than either alone. That was to related to mets not tissue sensitization to primary whole gland radiotherapy.

REPLY
1 reply
northoftheborder | @northoftheborder | 16 hours ago
In reply to @thmssllvn "Dr. Scholz also commented that 1st and 2nd generation ADTs work better than either alone. That..." + (show)
@thmssllvn

Dr. Scholz also commented that 1st and 2nd generation ADTs work better than either alone. That was to related to mets not tissue sensitization to primary whole gland radiotherapy.

Jump to this post

Did he possibly say ADT and the second generation ARSIs (ending in "-lutamide", like Apalutamide or Enzalutamide)? Those definitely work better together, as many studies have demonstrated.

They're all hormone therapy, but they work differently: ADT like Lupron or Orgovyx blocks testosterone production, while ARSI blocks testosterone reception by the cancer cells, so you're attacking it at both ends.

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