Undiagnosed progressive right leg atrophy

Posted by andeee @andeee, 1 day ago

Hello. This is my first post. I had a successful scoliosis revision surgery in 2021. Almost four years later, I began noticing painless right leg weakness with some cramping. I started weight training to strengthen the leg. The weakness grew worse. I returned to my surgeon and had imaging including MRIs, CT, Myelogram, X-rays. No abnormalities pointing to a cause. I’ve now seen multiple neurologists, had 2 EMGs, genetic testing, CSF testing, and bloodwork. Still no diagnosis. Now, almost a year after my first symptom, I am unable to walk without a walking stick and I cannot ascend stairs. I’ve fallen multiple times due to my right leg buckling. No injuries. Every doctor says this is a mystery. As such, I’ve received no treatment except PT scripts. Any and all hypotheses welcome!

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I should add the most recent EMG: This is an abnormal study. There is electrophysiologic evidence of a predominantly motor neurogenic process with active and chronic denervation in the right leg, as may be seen with multi-level lumbosacral radiculopathy or focal motor neuron disease. Lumbosacral plexopathy could be considered given the low saphenous nerve response. The study does not meet electrodiagnostic criteria for lower motor neuron disease. Furthermore, there is no electrophysiologic evidence of a right focal mononeuropathy, large fiber polyneuropathy, or myopathy. Repeat study in 3-4 months.

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And an MRI of my lumbosacral plexus that followed the EMG was normal.

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