TSH is rising taking same dose Synthroid for no understandable reason

vondav, it could be changes in absorption levels.
Changes in other medications or supplements can lower absorption. Stomach issues can cause lower absorption. Age can lower absorption. When patients were switched to the generic synthroid some had altered absorption.
You are wise to try and figure it out before the appointment. best wishes.

@vondav
I have had thyroid suppression doses for over 30 yrs. My TSH did fluctuate at times. One thing to explore is when you are taking the meds and if you are taking other meds or vitamins etc with the synthroid .
They should be taken early each day, before any meds , vitamins or food/drink.
Hoping things are settling down for you.
Prayers!

@gently thanks for your input. Yes, I do realize other meds, supplements, and all that can alter the absorption, but nothing has changed. I did not think much of the aging thing, though. It has been 15 years, and I am no longer a spring chicken. lol That may be something to consider. Thanks.

@vondav, I'm not happy to have reminded you of ageing, expecially if you weren't thinking about it. I do think age is an overused, easy and inaccurate diagnosis by our healthcare providers. I take it back, with apology.
There is a weight based dosage formulation that I'm not going to mention.

I had a lobectomy and diagnosed with Hurthle Cell Carcinoma in 2022. I had a very large nodule, but never had any “thyroid issues” prior to this surgury. A short while after surgery, it was determined that I needed to go on medicine and I am still having a VERY difficult time getting regulated on the medications. Medication changes and dosage changes caused side effects that increased and decreased but were still hard to manage. I have not been able to get regulated….yet. (The side effects can be quite bad!)
Due to this situation, I have done a lot of research and spoken to pharmacists about medications. A pharmacist told me that the pharmaceutical company does not have to tell you if they change their product as long as they do not change the main ingredient…..they can change the fillers without any notification. She also told me that when a company changes their active ingredients they notify pharmacists however it is usually just a change in the leaflet that most patients don’t read.
A few months ago, Synthroid and another medication had a recall due to an error in the strength of their medication. I was told that if a persons medication was part of the recall, they would be contacted, however I never heard about the recall until I saw it on the news. If you get several months supply of your medication, maybe you should check on the recall.

Another possible issue could be where the medication for your prescription was from. My nephew takes medication for ADHD and after refilling his prescription he developed a very bad allergic reaction (I don’t recall what it was). When my sister called the doctor, they told her to check with the pharmacy to see if the distributor was the same from her previous prescriptions and they found out that it was different. The pharmacy gave him the same prescription with pills that came from the distributor that they had previously used and he was fine. My sister said that the pharmacy has his prescriptions flagged so that they only come from one specific distributor.

Although the issues “could” be something internal, it might be worth exploring the medication just in case it is causing changes in your blood tests.
Good Luck!

I had a lobectomy and diagnosed with Hurthle Cell Carcinoma in 2022. I had a very large nodule, but never had any “thyroid issues” prior to this surgury. A short while after surgery, it was determined that I needed to go on medicine and I am still having a VERY difficult time getting regulated on the medications. Medication changes and dosage changes caused side effects that increased and decreased but were still hard to manage. I have not been able to get regulated….yet. (The side effects can be quite bad!)
Due to this situation, I have done a lot of research and spoken to pharmacists about medications. A pharmacist told me that the pharmaceutical company does not have to tell you if they change their product as long as they do not change the main ingredient…..they can change the fillers without any notification. She also told me that when a company changes their active ingredients they notify pharmacists however it is usually just a change in the leaflet that most patients don’t read.
A few months ago, Synthroid and another medication had a recall due to an error in the strength of their medication. I was told that if a persons medication was part of the recall, they would be contacted, however I never heard about the recall until I saw it on the news. If you get several months supply of your medication, maybe you should check on the recall.

Another possible issue could be where the medication for your prescription was from. My nephew takes medication for ADHD and after refilling his prescription he developed a very bad allergic reaction (I don’t recall what it was). When my sister called the doctor, they told her to check with the pharmacy to see if the distributor was the same from her previous prescriptions and they found out that it was different. The pharmacy gave him the same prescription with pills that came from the distributor that they had previously used and he was fine. My sister said that the pharmacy has his prescriptions flagged so that they only come from one specific distributor.

Although the issues “could” be something internal, it might be worth exploring the medication just in case it is causing changes in your blood tests.
Good Luck!

@koh I replied a short while ago, and then looked into that recall that you mentioned. The recall was a generic form of Synthroid. I have never taken a generic because my doctor told me not to because the tablets may not be consistent. I did a little research on that, and that seems to be true. Could that potentially be the reason why you are having problems? The actual manufacturer of Synthroid that is not generic is Abbvie. You may want to check into it.

My blood work is pretty stable now after soaring last year. But I have a friend who has been on thyroid replacement for 30 years. She has blood work every 6 weeks because she has frequent ups and downs.

@sandy8043

Hi, I had a total thyroidectomy last July and I am also still having to have blood work every six weeks.
Having a hard time figuring out my happy dosage of levothyroxine. It seems my levels are either way too low or way to high.