Trimix injection good or bad idea?

Posted by jasonfarmer @jasonfarmer, Sep 17, 2023

59 years old. prostatectomy just over 3 months ago. Take daily 5mg tadalafil or 100mg sildenafil before intercourse . Successful only 2 times without vac pump. I am considering Trimix injections just not sure when or if I should. I would appreciate some insight from men who have used and when they started. No other treatments for cancer needed. Presently cancer free. 0 psa 2 blood test so far. I am thankful for what I have just want the best I can achieve. Thank you for any shared experiences good or bad.

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@spino
If you have issues with needles there there alternative ways to apply Trimix. Topical gel and gel inserted in the urethra
Jake

REPLY

Hello,
I had a RALP Procedure done in October of 2023. I am 69 years old had normal erections with an invigorating sex life prior to my surgery. Although some men say they had absolutely no incontinence or ED issues following their surgery. They are a clear minority based on all of the evidence and facts I’ve researched in addition to my own personal experience. My erections have been measurably compromised. However, over time I’ve been able to obtain about a 70% effective erection which is better than it was but not quite good enough for effective and satisfying sexual intercourse. The pills have not been effective for me. The vacuum device works but the ring which is required to maintain one’s erection is too uncomfortable for me. I tried the TRIMIX INJECTIONS and have been extremely happy with the results. I give myself an injection and within about 5-7 minutes I acquire a very reliable and sustainable erection. In short, it works great for me. I don’t have any concerns or anxiety about whether or not I will attain an erection suitable enough for satisfying sexual intercourse with my wife. She definitely prefers a stronger, harder and reliable erection!
My advice is to try it and see how effective it can be for you. That’s really the only way to
find out. The injections are only the slightest bit uncomfortable and the minor discomfort I experience only lasts for a few minutes. Frankly, the results are so good for me that I don’t even think about the injections. It does take some experience to make a correct injection but this is accomplished in a very short period of time. There are some great videos on the internet that takes you step by step through the process. I just love the confidence they give me knowing that my erection will be there when I need it and it can last for up to an hour or more but generally lasts shorter than that. You also need to find the most effective dosage for your personal needs, (how much to inject)!
Occasionally I have missed the mark and caused a little bit of bruising but it’s so infrequent that it’s not any kind of real issue to deal with. Obviously, you need to be mindful regarding the sanitary requirements using alcohol to clean your penis and the vial you extract the TRIMIX from. It’s best to keep the TRIMIX frozen to maintain its potency..
I actually fill about 5 syringes, place them back in the freezer and pull one out about 10 minutes before I want to inject. The TRIMIX thaws out within several minutes while holding the syringe in your hands. The needle on the syringe is very small and similar to the size of needle used by diabetics to inject their insulin. The above tips are a few things I’ve learned along the way to make the entire process more simple and effective.
As you can see, I can’t recommend it highly enough if you aren’t having as much success as you would like utilizing the other methods available to assist with your erections etc.
Best wishes and good luck. If you end up trying it, I would like to hear about your experience and results.
Phil

REPLY
@philipsnowdon

Hello,
I had a RALP Procedure done in October of 2023. I am 69 years old had normal erections with an invigorating sex life prior to my surgery. Although some men say they had absolutely no incontinence or ED issues following their surgery. They are a clear minority based on all of the evidence and facts I’ve researched in addition to my own personal experience. My erections have been measurably compromised. However, over time I’ve been able to obtain about a 70% effective erection which is better than it was but not quite good enough for effective and satisfying sexual intercourse. The pills have not been effective for me. The vacuum device works but the ring which is required to maintain one’s erection is too uncomfortable for me. I tried the TRIMIX INJECTIONS and have been extremely happy with the results. I give myself an injection and within about 5-7 minutes I acquire a very reliable and sustainable erection. In short, it works great for me. I don’t have any concerns or anxiety about whether or not I will attain an erection suitable enough for satisfying sexual intercourse with my wife. She definitely prefers a stronger, harder and reliable erection!
My advice is to try it and see how effective it can be for you. That’s really the only way to
find out. The injections are only the slightest bit uncomfortable and the minor discomfort I experience only lasts for a few minutes. Frankly, the results are so good for me that I don’t even think about the injections. It does take some experience to make a correct injection but this is accomplished in a very short period of time. There are some great videos on the internet that takes you step by step through the process. I just love the confidence they give me knowing that my erection will be there when I need it and it can last for up to an hour or more but generally lasts shorter than that. You also need to find the most effective dosage for your personal needs, (how much to inject)!
Occasionally I have missed the mark and caused a little bit of bruising but it’s so infrequent that it’s not any kind of real issue to deal with. Obviously, you need to be mindful regarding the sanitary requirements using alcohol to clean your penis and the vial you extract the TRIMIX from. It’s best to keep the TRIMIX frozen to maintain its potency..
I actually fill about 5 syringes, place them back in the freezer and pull one out about 10 minutes before I want to inject. The TRIMIX thaws out within several minutes while holding the syringe in your hands. The needle on the syringe is very small and similar to the size of needle used by diabetics to inject their insulin. The above tips are a few things I’ve learned along the way to make the entire process more simple and effective.
As you can see, I can’t recommend it highly enough if you aren’t having as much success as you would like utilizing the other methods available to assist with your erections etc.
Best wishes and good luck. If you end up trying it, I would like to hear about your experience and results.
Phil

Jump to this post

I did have one experience of freezing the vial and then after thawing something precipitated out--turned to crystals. I was still able to use the remainder of the vial (increasing the dosage to compensate,) but the pharmacist told me this can happen, depending on some (uncontrollable by me) factors in how it was mixed, and that I should not freeze it. I have gone with her advice since then.

REPLY
@spino

I did have one experience of freezing the vial and then after thawing something precipitated out--turned to crystals. I was still able to use the remainder of the vial (increasing the dosage to compensate,) but the pharmacist told me this can happen, depending on some (uncontrollable by me) factors in how it was mixed, and that I should not freeze it. I have gone with her advice since then.

Jump to this post

Hi Spino,
There’s the possibility that when you inserted the needle into your TRIMIX vial to withdraw multiple dosages over time that you were going in at the same location of the rubber top which made the hole a little bigger than usual allowing some of the pressurized TRIMIX to escape and bubble etc. I insert pressurized air in the same amount as my dose into the vial before extracting my dosage to make a more smooth and constant flow when filling my syringe.
Due to the fact that this is a compounded medication it’s not always formulated exactly the same by every compounding pharmacy that does it,
You’re correct in the normal instructions regarding storage temperature that to adjust your refrigerator down to the recommended parameters it should be cold enough to store your TRIMIX.
That’s what I had been doing for my first 3 vials.
I spoke with my pharmacist to discuss the “freezing vs the storage in the refrigerator” method as to which was best!
She informed me that based upon the testing they had done and what had also been done and tested by independent sources that tested their TRIMIX formula that it held its overall potency better and longer if kept in a “frozen state!”
I am not sure if there is an absolute correct answer here. My personal choice going forward is to “freeze” it. I found that my TRIMIX did loose some of its potency and strength over time when only “refrigerated!”
Like most things when it comes to all things “Prostate Cancer” related etc. There are different approaches in the treatments and recovery methodologies used by different patients.
That’s my read on the situation.
Best wishes and good luck on your journey.
Phil

REPLY
@philipsnowdon

Hi Spino,
There’s the possibility that when you inserted the needle into your TRIMIX vial to withdraw multiple dosages over time that you were going in at the same location of the rubber top which made the hole a little bigger than usual allowing some of the pressurized TRIMIX to escape and bubble etc. I insert pressurized air in the same amount as my dose into the vial before extracting my dosage to make a more smooth and constant flow when filling my syringe.
Due to the fact that this is a compounded medication it’s not always formulated exactly the same by every compounding pharmacy that does it,
You’re correct in the normal instructions regarding storage temperature that to adjust your refrigerator down to the recommended parameters it should be cold enough to store your TRIMIX.
That’s what I had been doing for my first 3 vials.
I spoke with my pharmacist to discuss the “freezing vs the storage in the refrigerator” method as to which was best!
She informed me that based upon the testing they had done and what had also been done and tested by independent sources that tested their TRIMIX formula that it held its overall potency better and longer if kept in a “frozen state!”
I am not sure if there is an absolute correct answer here. My personal choice going forward is to “freeze” it. I found that my TRIMIX did loose some of its potency and strength over time when only “refrigerated!”
Like most things when it comes to all things “Prostate Cancer” related etc. There are different approaches in the treatments and recovery methodologies used by different patients.
That’s my read on the situation.
Best wishes and good luck on your journey.
Phil

Jump to this post

Hi back at you, Phil. Yes, what you are saying was what I had been going on when i started freezing it. The first time worked fine. The second time not so much. I agree with your comments about technique. I haven't had any trouble with trimix escaping or bubbling when I do it as you indicate. I'm glad trimix is available, and while not perfect, it's been a valuable aid, although my wife did comment last night that she wasn't worried about me getting too aggressive with her because I didn't have a shot nearby.... We both found it funny in an ironic sort of way. Life's journey has lots of unanticipated lessons to teach along the way.
Regarding the loss of potency, it turns out there is only one of the three chemicals in the trimix that loses its potency and that is fairly measured, like 20% over six months when kept consistently refrigerated at a temp between 40F and 32F (normal for food storage). I am at around 200 shots now over 21 months and am 2 months into using my fourth vial. At $100 a vial, that's a lot more cost effective than using a vial every month, and ultimately it's just a short term effect each time. Of course, safety is paramount.

REPLY

I notice only brief references to cost. Perhaps does anyone know if TRIMIXis covered by Tricare prescription coverage? I can also look in the formulary. Thx.

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I pay 150 for a bottle of Trimix this includes FedEx overnight shipping with cold pack from a sterile compounding pharmacy. It is @ 15 injections . I did not have insurance that would cover it. It is well worth the cost to me. I do get a pack of 10 syringes included with order.

REPLY
@glenallen

I notice only brief references to cost. Perhaps does anyone know if TRIMIXis covered by Tricare prescription coverage? I can also look in the formulary. Thx.

Jump to this post

No plan I know covers trimix. Also I believe it is not FDA approved as is, since it involves mixing three medicines.
I was originally directed to an online source in FL. The first time the med was delayed and arrived no longer cold. It still worked, but I thought, "Wouldn't it be better to get it locally?" So I called around and found there was a compounding pharmacy (one) in our urban area =< 1 million that would make it up for me. It ended up actually being cheaper when including all the costs. I go to the pharmacy and they mix it after I arrive while I wait. It costs right at $100 per vial. Number of doses is dependent on dose of course, but let's say possibly between 50 and 100, so it's limited by shelf life of the medicine. If you follow the pharmacy guidelines to use it in a month, that might be 15 or fewer doses. As I noted elsewhere, I use it for about 5 months. That means my cost is about $1.50 per dose including the needles, rather than >$6. While I also get 10 needles with it, I buy needles from Amazon in batches of 100 for $17, so it's a fairly trivial expense and I get consistent needles.

REPLY
@spino

No plan I know covers trimix. Also I believe it is not FDA approved as is, since it involves mixing three medicines.
I was originally directed to an online source in FL. The first time the med was delayed and arrived no longer cold. It still worked, but I thought, "Wouldn't it be better to get it locally?" So I called around and found there was a compounding pharmacy (one) in our urban area =< 1 million that would make it up for me. It ended up actually being cheaper when including all the costs. I go to the pharmacy and they mix it after I arrive while I wait. It costs right at $100 per vial. Number of doses is dependent on dose of course, but let's say possibly between 50 and 100, so it's limited by shelf life of the medicine. If you follow the pharmacy guidelines to use it in a month, that might be 15 or fewer doses. As I noted elsewhere, I use it for about 5 months. That means my cost is about $1.50 per dose including the needles, rather than >$6. While I also get 10 needles with it, I buy needles from Amazon in batches of 100 for $17, so it's a fairly trivial expense and I get consistent needles.

Jump to this post

Great info; thx. I’m just beginning this long and winding road, but this appears to be a great solution.

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