Treating SJOGREN'S: Anyone used Low Dose Naltrexone?

Hello @ginger55, welcome to Connect. You will notice that we added a little to your discussion title to help members who have tried low dose naltrexone (LDN) find and share their experience with you. I'm tagging @deborahyost3 and @suetex who have posted in other discussions about using LDN for treating Sjogren's.

While you wait for other members to respond I thought you might find it helpful to scan through the following discussion to learn what others have shared:
-- Sjögren’s Syndrome: how do you manage the symptoms?
https://connect.mayoclinic.org/discussion/sjorgens-syndrome/

Hi. I have Sjogren’s disease but I was started on LDN before the neuroblock was placed for my TN. I suffer from different types of neuropathy with this Sjogren’s disease. The explanation that I was given by my pain/anesthesia specialist is that my nerves are in haywire and it will help the neuroblock to work well.
I do still deal with severe pain daily even with the LDN and methotrexate. I think it’s a combination of my Sjogren’s arthritis, severe osteoarthritis, and my hypermobile joints.

Hi, @ginger55, glad to sing the paises of LDN. If you any lessining of the immune system give it a try. I know it works great for diarrhea and Crohn's. I was already on it when I found a doc that knew enough about Sjogren's to diagnose it so it would be hard to tell what effect LDN had on the Sjogren's. I know it was resposible for healing my small intestine. And that is enough reason for me.

@josmio Sorry for your pain and I can truly empathize. I wonder if you have had a bad reaction of any negative side effects ,with your taking methotrexate, since my rheumatologist suggested this med in place of Plaquenil, which gave me severe migraines? The pitfall of most meds are in addition to the so called ' benefits', there is always a negative side effect which varies with each invidual body chemistry.

@suetex Thank you for your response. I started on 1.5, mg, LDN, then a week later 3 mg, then the third week 4.5 mg which proved very horrific as it gave me NO ENERGY at all and could not function, I then reverted back for a month to 3 mg, which was better but eventually gave me headaches and stomach aches. So I wondered which quantity of LDN you were on.?? I think the amount should be elevated slowly, as the body needs adjustment. So glad to hear your small intestine was healed with LDN, which makes me feel more positive about sticking it out and be patient.