Transdermal HRT

Posted by vkmov @vkmov, Oct 19, 2023

Many studies have found that transdermal HRT protects and builds bone without all the horrific side effects of many first-line osteoporosis treatments. The patch bypasses the liver and thereby avoids the risks of breast cancer, strokes, etc. Has anyone explored this or discussed it with their doctors?

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

@mayblin

Hi @pennykj , great to hear that your dxa held stable in the past year. May I ask the main reason that your obgyn advices against hrt in your case? Your reduction in ctx is remarkable. What do you think is the main contributing factor? Did you have your p1np tested as well? Thanks a lot!

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My gyn pretty much said that I was too old to start (too long past menopause). She thought there was a risk of blood clots. However, she said she would prescribe if I insisted and got clearance in writing from my cardiologist. My p1np was not retested in April 2024, but will be retested in 2025.
I have no idea what was the main contributing factor since I was doing so much (no alcohol, no caffeine, no sugar, Marodyne vibration plate, quality supplements, weight training, yoga, walking, protein powder, collagen, better sleep).

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@pennykj

My gyn pretty much said that I was too old to start (too long past menopause). She thought there was a risk of blood clots. However, she said she would prescribe if I insisted and got clearance in writing from my cardiologist. My p1np was not retested in April 2024, but will be retested in 2025.
I have no idea what was the main contributing factor since I was doing so much (no alcohol, no caffeine, no sugar, Marodyne vibration plate, quality supplements, weight training, yoga, walking, protein powder, collagen, better sleep).

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I see. Thank you for replying and sharing your secrets of success. Whatever you are doing is working great!

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@hopefullibrarian

Hi mayblin, I'm starting on a very small dose of .05/0.14 mg per day with a plan to increase it gradually because I have epilepsy. My BTMs were tested in January, and will be done again next month. I'm also on Evenity, so it's being done primarily to monitor that. With the addition of HRT, I'm going to request it again for July. So, I guess, to answer your last question, the BTMs are being done every 3 months.

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Hi, @hopefullibrarian It looks like we have chosen a similar path. I had my first Evenity injections in October, and I started the .05 Estradiol patch the next day. I’m curious if you’ve had any bone marker tests since adding the HRT to the mix. If so, would you mind commenting on your results?

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