Possible Creon side effects: What helped you?

Posted by ajh5285 @ajh5285, Feb 14, 2023

I have a variety of Side Effects that are all listed as possibly related to Creon, the most troublesome being gas which seems to last hours. The NP I saw in the last week or so invited me to make a trial of not taking any Creon to see what happens.

Has anyone else had any experience with this approach?
Would you recommend it?

If I were healthy, I would be more willing to be adventurous...

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Profile picture for stageivsurvivor @stageivsurvivor

For bloating and gas, the OTC products Phazyme and Gad-X with Simethicone are helpful. If consuming high-fiber vegetables like broccoli, peas, corn, cabbage, cauliflower, Brussels sprouts, they require the enzyme alpha-d-galactosidase for digesting them. It is not blended into any pancrealipase. The OTC product Beano is alpha-d-galactosidase and will prevent gas.

One 36K capsule might not be enough enzymes for your particular diet. An on-line dosing calculator will be helpful in determining the amount of pancrealipase required.
https://digestthis.ca

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The blurred vision showed my pupil is somewhat dilated by the Creon. Anyone else has this side effect and how to deal with it?

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Profile picture for henfayp @henfayp

I am taking Creon 36000 per meal for two weeks now and now I have blurred vision, one of the side effects lists also bloating and gas. How does one handle these?

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I also have blurred vision I think is side effect

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Profile picture for crickard70 @crickard70

I also have blurred vision I think is side effect

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Did you see an eye doctor to see what can be done? I am making an appointment with my eye doctor.
Anyone else has this problem and how did you deal with it?

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Tongue with a burning sensation and tingling started about 6 weeks ago. Have seen internist, gastro and dentist. None saw anything alarming. Take CREON for EPI and gastro told me a reaction to that usually starts when you first start this medication or for people who may chew the capsules (which you aren't supposed to do). Also have loud ringing in the ears. Read tongue issue can be vitamin deficiency, so added B Complex, Potassium, Niacin, Folic Acid and 10 mg liquid Iron, as my Ferratin was low, Started taking all over a month ago. There is one place on L side of tongue that is irritated and gets worse as the day goes on. Back to the dentist tomorrow to have him check to see if I have somehow chipped a crown and it is irritating tongue. Have an appointment with ENT, so she can have a look, as I know this is a process of elimination. My plan is to ask for an MRI of head and neck if I can't get this resolved, but with current complaint burning/tingling in tongue and nothing visible, I know a doctor will not prescribe, although I will pay myself if I have to, but still need orders from doctor. Also started taking Pepcid three days ago in case it is acid reflux, which I have had in the past.
Hope my Mayo Connect friends can help me figure this out. Thanks to all who read and respond.

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Profile picture for penelope52 @penelope52

Tongue with a burning sensation and tingling started about 6 weeks ago. Have seen internist, gastro and dentist. None saw anything alarming. Take CREON for EPI and gastro told me a reaction to that usually starts when you first start this medication or for people who may chew the capsules (which you aren't supposed to do). Also have loud ringing in the ears. Read tongue issue can be vitamin deficiency, so added B Complex, Potassium, Niacin, Folic Acid and 10 mg liquid Iron, as my Ferratin was low, Started taking all over a month ago. There is one place on L side of tongue that is irritated and gets worse as the day goes on. Back to the dentist tomorrow to have him check to see if I have somehow chipped a crown and it is irritating tongue. Have an appointment with ENT, so she can have a look, as I know this is a process of elimination. My plan is to ask for an MRI of head and neck if I can't get this resolved, but with current complaint burning/tingling in tongue and nothing visible, I know a doctor will not prescribe, although I will pay myself if I have to, but still need orders from doctor. Also started taking Pepcid three days ago in case it is acid reflux, which I have had in the past.
Hope my Mayo Connect friends can help me figure this out. Thanks to all who read and respond.

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I have had geographic tongue and burning mouth syndrome for years. Supposedly no cure, take lots of vitamins, mucosal membranes missing so everything with spice or acid stings. Maybe autoimmune disorder but no one seems to know!! Super frustrating….

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Profile picture for penelope52 @penelope52

Tongue with a burning sensation and tingling started about 6 weeks ago. Have seen internist, gastro and dentist. None saw anything alarming. Take CREON for EPI and gastro told me a reaction to that usually starts when you first start this medication or for people who may chew the capsules (which you aren't supposed to do). Also have loud ringing in the ears. Read tongue issue can be vitamin deficiency, so added B Complex, Potassium, Niacin, Folic Acid and 10 mg liquid Iron, as my Ferratin was low, Started taking all over a month ago. There is one place on L side of tongue that is irritated and gets worse as the day goes on. Back to the dentist tomorrow to have him check to see if I have somehow chipped a crown and it is irritating tongue. Have an appointment with ENT, so she can have a look, as I know this is a process of elimination. My plan is to ask for an MRI of head and neck if I can't get this resolved, but with current complaint burning/tingling in tongue and nothing visible, I know a doctor will not prescribe, although I will pay myself if I have to, but still need orders from doctor. Also started taking Pepcid three days ago in case it is acid reflux, which I have had in the past.
Hope my Mayo Connect friends can help me figure this out. Thanks to all who read and respond.

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I had intermittent burning in the back of my throat. Wasn’t sure what it was. Stopped acidic food, went on pepcid and it did stop, but I don’t think it was reflux. Never had reflux before. No burning in chest or indigestion.

I’ve resumed some acidic foods, stopped Pepcid with no recurrence of burning, so…idk.

I have post covid syndrome. I feel it’s related to that, but have no proof. But, I had recently been diagnosed and treated for Vitamin B12 deficiency.

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Profile picture for penelope52 @penelope52

Tongue with a burning sensation and tingling started about 6 weeks ago. Have seen internist, gastro and dentist. None saw anything alarming. Take CREON for EPI and gastro told me a reaction to that usually starts when you first start this medication or for people who may chew the capsules (which you aren't supposed to do). Also have loud ringing in the ears. Read tongue issue can be vitamin deficiency, so added B Complex, Potassium, Niacin, Folic Acid and 10 mg liquid Iron, as my Ferratin was low, Started taking all over a month ago. There is one place on L side of tongue that is irritated and gets worse as the day goes on. Back to the dentist tomorrow to have him check to see if I have somehow chipped a crown and it is irritating tongue. Have an appointment with ENT, so she can have a look, as I know this is a process of elimination. My plan is to ask for an MRI of head and neck if I can't get this resolved, but with current complaint burning/tingling in tongue and nothing visible, I know a doctor will not prescribe, although I will pay myself if I have to, but still need orders from doctor. Also started taking Pepcid three days ago in case it is acid reflux, which I have had in the past.
Hope my Mayo Connect friends can help me figure this out. Thanks to all who read and respond.

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Interesting…thanks for posting. Please read below.

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Profile picture for penelope52 @penelope52

Tongue with a burning sensation and tingling started about 6 weeks ago. Have seen internist, gastro and dentist. None saw anything alarming. Take CREON for EPI and gastro told me a reaction to that usually starts when you first start this medication or for people who may chew the capsules (which you aren't supposed to do). Also have loud ringing in the ears. Read tongue issue can be vitamin deficiency, so added B Complex, Potassium, Niacin, Folic Acid and 10 mg liquid Iron, as my Ferratin was low, Started taking all over a month ago. There is one place on L side of tongue that is irritated and gets worse as the day goes on. Back to the dentist tomorrow to have him check to see if I have somehow chipped a crown and it is irritating tongue. Have an appointment with ENT, so she can have a look, as I know this is a process of elimination. My plan is to ask for an MRI of head and neck if I can't get this resolved, but with current complaint burning/tingling in tongue and nothing visible, I know a doctor will not prescribe, although I will pay myself if I have to, but still need orders from doctor. Also started taking Pepcid three days ago in case it is acid reflux, which I have had in the past.
Hope my Mayo Connect friends can help me figure this out. Thanks to all who read and respond.

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I had some of the same tingling issues . I also had tingling sensations especially in chin area . I think for me is an allergic reaction to the Pepcid,pantaprazole which is famotidine. I stopped the meds and tingling went away.I also had burning tongue but ent thought it was a vitamin deficiency. Hope this helps. I believe I have a sensitive esophagus because of the acid.I have read about this that People take some type of med to relax nerves called amitriptyline.Haven't tried it.Sometimes I feel a tickle,reactions to hot or certain foods that I must have a sensitivity to. Hard to explain but ppis don’t help. I have to watch what I eat, how much and when…I take reflux gourmet at night or when I start coughing due to going off the diet. I follow Dr . Jamie Koufman diet and Jonathan Aviv on Facebook. Lots of great advice.Good luck.

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Profile picture for staceywood @staceywood

I have had geographic tongue and burning mouth syndrome for years. Supposedly no cure, take lots of vitamins, mucosal membranes missing so everything with spice or acid stings. Maybe autoimmune disorder but no one seems to know!! Super frustrating….

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Thanks that's what I am beginning to figure out.

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Profile picture for cj16 @cj16

I had some of the same tingling issues . I also had tingling sensations especially in chin area . I think for me is an allergic reaction to the Pepcid,pantaprazole which is famotidine. I stopped the meds and tingling went away.I also had burning tongue but ent thought it was a vitamin deficiency. Hope this helps. I believe I have a sensitive esophagus because of the acid.I have read about this that People take some type of med to relax nerves called amitriptyline.Haven't tried it.Sometimes I feel a tickle,reactions to hot or certain foods that I must have a sensitivity to. Hard to explain but ppis don’t help. I have to watch what I eat, how much and when…I take reflux gourmet at night or when I start coughing due to going off the diet. I follow Dr . Jamie Koufman diet and Jonathan Aviv on Facebook. Lots of great advice.Good luck.

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Thanks for the diet tips will those look up those two.

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