It’s been 5 years since my Carcinoid was removed from my colon (Ilium). At that time, they found it had also spread to 2 of the 19 lymph nodes. My only symptoms then was severe watery diarrhea and occasional flushing. About 9 months ago, I started having frequent flushing and some diarrhea. The flushing has gotten very bad (multiple episodes a day) and my fatigue is severe last 3 months. All of my scans are normal. Tumor markers go up a little, but had been still within normal limits (other than occasional very minor high result for Chromogranin-A due to GERD PPI meds) until this last draw. This time, my Chromogranin-A was very high at 1410 and my Pancreastatin was high at 155. My local oncologist said could be an anomaly with the lab, but it seems too odd that 2 are so high, especially with my symptoms. My other oncologist said that often these tumor markers show up way before anything reveals itself on scans, so it is a wait and see game. Has anyone else experienced this? It’s so emotionally draining. Any recommendations on how to get through this without over reacting would be much appreciated. My tumor was classified as “Well-differentiated” with pathologic stage of: T2 N1 M0. it surprised all of my docs that it spread even though low grad and well-differentiated, which is why I worry something is being missed.