Testosterone as fuel, let's think about it together ...

Posted by denis76 @denis76, Mar 7 7:10am

Friends, I'm curious about your thoughts on the best strategy to keep testosterone levels low.

I'll share what I've read and the conclusions I've reached (they may be wrong), and I invite your opinions!

1. It's clear that testosterone is fuel. I've read that malignant cells produce testosterone themselves. Do you think this is true?

2. For a year, I had a problem – my testosterone wasn't dropping, and I was ready to have my balls amputated. It's worth noting that during this period (after chemotherapy, for about a year and a half, it was slowly increasing), I was very active (running, exercising). I decided to test one hypothesis (the more you move, the more testosterone is produced because it's used by the muscles). I abruptly stopped moving, which led to a sharp drop in my testosterone levels.

3. By lowering testosterone levels, we inhibit the pathways for testosterone synthesis, right? There are also a number of foods that inhibit testosterone synthesis, such as licorice root and green tea. They should be consumed regularly.

4. Testosterone has competitors in the body – other hormones. I've read that elevated cortisol lowers testosterone, and the same applies to prolactin.

This raises several questions.

a) Should we believe that physical activity is good? During exercise, muscles require glycogen (produced by the liver) and testosterone. Now, consider this: if cancer cells themselves produce testosterone, aren't we shooting ourselves in the foot? Training to the point of exhaustion, when we're exhausted, is a different matter.

b) Does excess weight or thinness affect testosterone production? Many of you have attended meetings attended by guys who have successfully battled this disease for years, and I wonder what they're like? Fat or thin, do a lot of exercise, or sit in a chair.

I just want to find a pattern! I feel like I'm wasting my time in a chair (I've gained 10 kg) and I need to get back into active exercise, but I'm afraid my testosterone will start to spike again.

Jeff, I wanted to hear you talk about being a monster who's been successfully fighting the black spider for 16 years! Amazing!

And the rest of you guys, I'm really curious what you think about this.

Thank you all! I wish you all success!

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

I agree: avoid black licorice.

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@stage4lovolmetpc

mmm.

After Docitaxel, my doctor prescribed ADT—an injection every three months (Zolodex 10.8). After seven months, my testosterone levels began to rise, and I was prescribed a different drug and a more aggressive method—one every 28 days. My testosterone levels slowly plateaued, and it was at that point that I intuitively decided to reduce my physical activity, which led to a sharp drop in my testosterone levels by 1.5 times.

My doctor said the new ADT is cumulative. Furthermore, I should note that my PSA level, after chemotherapy and on my previous ADT, had plateaued at 6.2 and didn't drop until Erleada and the switch to the other ADT. Plus, almost in despair, I began reducing my physical activity and drinking green tea and licorice root in huge quantities. And finnally I lowered my cholesterol levels several times and my lipids (they returned to normal) by starting to take statins. In a panic, I did something else, I don’t remember what.

A month ago, I had my biochemistry tests done, and my doctor said the results were excellent (knock on wood).

Of course, I admit that the decrease in testosterone isn't related to physical activity and is a result of the more aggressive ADT, but testosterone levels fluctuate throughout the day. They peak early in the morning and begin to decline throughout the evening. My last testosterone test was at 9 a.m., and each time, I took it at the same lab.

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@denis76 Be careful with licorice root. Too much of it can cause atrial fibrillation if you're prone to it.

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