Anyone taking Tagrisso for Lung Cancer?

@glendap56, welcome to Mayo Connect. It's great to hear that Tagrisso is proving to be effective for you. I hope that continues for many years. I'll be interested to hear what others have to say regarding vitamins and supplements.
I take a different targeted therapy, for a different gene mutation, ALK. I don't take much other than the occasional vitamin C or multi vitamin. In the past I have noticed that taking some supplements have had a negative impact on my liver or kidney counts. Be sure to check with your oncologist and keep an eye on those numbers if you start taking more. Did you take many supplements before cancer?

I’ve been taking Tagrisso for 4 months now for NSCLC stage 4 and doing very well. My last CT in January showed my tumour had shrunk and the associated lymph nodes and pleural effusion had all shrunk as well! I’m very interested to know which vitamins you take as I’m keen to start helping my immune system with supplements which won’t interfere with Tagrisso. Thanks very much.

@babs1956, Tagrisso has been the proverbial godsend for those of us with certain types of EGFR mutation. It's a small molecule targeted therapy that has dramatically extended both PFS (progression-free survival) and OS (overall survival). My lung cancer (LC) metastasized to my brain in 2020, which is when I started Tagrisso. Four and a half years later, I'm still doing well on it and am currently cancer-free. I have two friends who have been on it for over 7 years and are both still active. One is a personal trainer!

My experience with Tagrisso is that the initial side effects, like the ever-popular diarrhea, die off after a few months. That's how long it takes the body to adapt to it. Hopefully, your side effects will also disappear over time.

The one thing I learned later that I wish I'd known early is that the most important thing is to decide what time of day to take it and then stick to that time to maintain a constant level of the drug in your body. Initially, I chose two hours after breakfast and two hours before lunch, and that's still when I take it. Consistent time is more critical with some people than with others, but it turned out I'm one of those people. I had a slight recurrence about a year ago that we successfully treated with 1 round of targeted radiation. My friend Larry had a similar experience. Neither of us has had any other recurrence since the first one.

Targeted therapy is the future of lung cancer treatment; new ones are being developed almost daily! It's actually a challenge to keep up with them all. You can learn more at lungevity.com, go2.org, and, if you're ready for a deep dive, you can join the International Association for the Study of Lung Cancer and see the same information your oncologist is reviewing. Lungevity and GO2 are much more user-friendly. 🙂

Welcome to the club no one wants to belong to, where there are more of us living our lives with lung cancer than ever before.

I’m so happy to hear that your nails and hair are doing great. That’s wonderful. Right now Tagrisso is the only meds I’m taking I take a lot of vitamins, my oncologist knows all the vitamins I take and he said they’re good. They wouldn’t interfere with Tagrisso. Thank you so much.

I’ve been on 40 mg since July 2023. 80 mg caused serious skin issues. I looked like one big red bump. Some
People have great longevity on Tagrisso. Others, not so much. We go from CT scan to CT scan hoping for the best.

@babs1956, Tagrisso has been the proverbial godsend for those of us with certain types of EGFR mutation. It's a small molecule targeted therapy that has dramatically extended both PFS (progression-free survival) and OS (overall survival). My lung cancer (LC) metastasized to my brain in 2020, which is when I started Tagrisso. Four and a half years later, I'm still doing well on it and am currently cancer-free. I have two friends who have been on it for over 7 years and are both still active. One is a personal trainer!

My experience with Tagrisso is that the initial side effects, like the ever-popular diarrhea, die off after a few months. That's how long it takes the body to adapt to it. Hopefully, your side effects will also disappear over time.

The one thing I learned later that I wish I'd known early is that the most important thing is to decide what time of day to take it and then stick to that time to maintain a constant level of the drug in your body. Initially, I chose two hours after breakfast and two hours before lunch, and that's still when I take it. Consistent time is more critical with some people than with others, but it turned out I'm one of those people. I had a slight recurrence about a year ago that we successfully treated with 1 round of targeted radiation. My friend Larry had a similar experience. Neither of us has had any other recurrence since the first one.

Targeted therapy is the future of lung cancer treatment; new ones are being developed almost daily! It's actually a challenge to keep up with them all. You can learn more at lungevity.com, go2.org, and, if you're ready for a deep dive, you can join the International Association for the Study of Lung Cancer and see the same information your oncologist is reviewing. Lungevity and GO2 are much more user-friendly. 🙂

Welcome to the club no one wants to belong to, where there are more of us living our lives with lung cancer than ever before.

I am one of the unlucky ones who developed pneumonitis after 7 weeks on Tagrisso. Super steroids cleared up the problem but I can't take it so waiting to see oncologist on the 6th for next plan of action. Totally bummed