Anyone taking Tagrisso for Lung Cancer?

I had to stop taking Tagresso 2 1/2 years ago. I took it & was fine for about 8 months. All of a sudden I got very sick. I might have been allergic to something. I still get a CT scan every 3 months. If you have to go off Tagresso for any reason, there are so many medicines that are available. I am not on any medication & in remission. You can be fine without it. Hugs!!

Like most in these threads the side effects are the norm, I just continue through. I was lucky that they removed half my left lung in January 2024 taking with it a Stage 3a adenocarcinoma with EGFR exon 19 and TP53 variant of NSCLC. Due to the spread in 4 lymph nodes I went through 4 cycles of chemotherapy and was lucky enough to go onto Tagrisso 80mg after the chemo.

I have been on this since June 2024 and I believe I have had many side effects, they cycle through on a regular basis. The diarrhea is constant, the lack of appetite is frustrating, cramps are unbelievable and my constant companion, my nails break continuously, toe pain similar to ingrown toe-nails but not, eye changes (I have a cataract growing and dry eyes), have many pimples on my face and arms, I constantly look purple and yellow wondering how did that happen (due to blood clots found when I broke my leg a month before finding out I had cancer, they took me off the blood thinners but following my 2nd chemo cycle I got 5 blood clots in my right lung so back on the thinners), heart races a lot, mouth ulcers, tired as I have difficulty sleeping.

BUT I am lucky to be having side effects, the alternative in not being here is not an option. I supplement tagrisso, eliquis and metoprolol with double magnesium chelate, vitamin D, ostelin calcium with D3 and K2, olive leaf extract, milk thistle (I have a lesion on my liver that they don't know what it is so I added this), bioflam (a natural anti-inflammatory as I am allergic to anti-inflammatories), betamax, KFibre, acacia root fibre, collagen and a menopausal powder (do get a bit cranky).

I was having an abdomin, chest and pelvic CT plus a brain MRI every 3 months, they have now replaced the CT with a 3 monthly PET scan. I do think a lot about what will happen after another 18 months of Tagrisso, when I come off the drug. My little devil on my shoulder annoys me every now and then but I keep telling him to shut up.

My whole family know that I am having a chocolate mud cake with a 100 candle on it, I have another 40 years to go to reach that goal. All the pain in the butt side effects annoy me but I push on because I want to be here, to see my grandchildren, retire with my husband ... my best friend ... so we can travel, I'm an Aussie and there is a lot of country to see over here. Life is so worth living that I will go through everything to be here. Keep being positive!

Thank you so much and I wish you so much. Good luck too Godspeed.

Yeah, my oncologist gave me prescription for Clindamycin Phosphate Topical Solution. A small amount on my nose and infected area worked great. Radical Remission is another good read. I just went back and revisited that book and a lot of things made more sense now that I’ve been on this journey for four months. All of my original symptoms have eased and I just live as I always have. I’m still active with no breathing issues. I don’t want to get ahead of myself until I get my first CT scan, but I’m trying to live my normal active lifestyle.

I’m sorry to hear about the radiation treatment. I hope you do well and it is successful. I’m on 80mg and thankfully only small issues. I am doing more toxicity testing in a few days to check on the metals remaining in my body - mostly uranium. We all have some I know, but my results were off the charts. Not saying that is the cause for my lung cancer, but uranium is known for its contribution. I’m hoping my CT Scan shows improvement or at least no growth or spread. But I am prepared for more aggressive treatment if need be. I wish you luck.

I lived in an industrial town where they made an orange for Vietnam. Also Hills Brothers coffee was here the Ford plant. So I’ll be needing radiation. It seems like the Tagrisso is working, but I’m still getting nodules but they’re growing very slowly. I’m having radiation on one Nodule. It went from 1.1 cm to 1.6 cm. I’m taking 40 mg if Tagrisso. I can’t take the 80mg. I get all these bruises on my legs

Stock, sounds like we are on a similar path. I too have pimples, funny as a teenager I was embarrassed now I couldn’t care less I had a spot on my left frontal lobe and right femur. I’m able to do most things as I had before other than shortness of breath. Have found Dr Li’s book very helpful. We should chat more.

I’m so happy you’re doing well on Tagrisso. I took 80 but my legs got all bruises on them so he lowered the dose to 40.

i take 80mg Tagrisso. I havent had many bad reactions yet. At first it made me tired, then pimples on my nose and chin. I really enjoyed a podcast I listened to a few months back with Dr Li. I then bought his book, "Eat to beat disease".

No, but I'm planning on getting one. Sounds really good. Thanks!