Would be beyond grateful for any insight or advice regarding BMES, as my research efforts have been largely fruitless. Very little is medically understood about the condition and I have been suffering with debilitating, severe pain in my left ankle for exactly two years. Hoping to avoid a core decompression surgery, but it may be necessary of enough damage has been done due that the fluid can cause (nerve damage, blood flow, bone collapse, etc.). Is there anyone out there who might shed some light on Bone Marrow Edema Syndrome? I’d travel anywhere to participate in any such study.