1. < Prostate Cancer

Stage 4 PC Longevity: Anyone have prostate cancer more than 10 years?

Posted by ringmastr1 @ringmastr1, May 26, 2023

There is a lot of great info on this forum. I am 54 and was just diagnosed in January with metastatic Stage 4 PC. (Hip, L4, Sacrum, and a small liver lesion). My PSA has gone from 359 in January to .24 last week and I feel great! I am curious to know how many guys on this forum have been treated for more than 10 years and what your quality of life is like. It is stories like this that will give me (and others) more hope. Peace to you all!!!

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

proftom2 | @proftom2 | 2 days ago

I'm just entering year 5. Became resistant 12 months ago, and started Pluvicto 1/27/25. Injection every 6 weeks. Slight PSA decrease after first injection, after 12 months of steady PSA rising a slight down tick works great for me.

REPLY
amee | @amee | 2 days ago
In reply to @melcanada "Nothing can cure mets to the bones, just control it Kill of many calls but it..." + (show)
@melcanada

Nothing can cure mets to the bones, just control it Kill of many calls but it hands around
Radium 225 is similar but different LU has radium from Nuclear plant and formulated a few days before the injection That is why one must not miss appointment
I posted this in 2024 This too is valuable
https://airomedical.com/blogs/treatment-guides/what-is-better-actinium-radium-or-lutetium-for-prostate-cancer

Jump to this post

Thank you, read the link you shared that is quite helpful.

REPLY
melcanada | @melcanada | 2 days ago
In reply to @amee "Can lu 177 or Radium 223 can cure Prostate cancer which has spreaded to the bones...." + (show)
@amee

Can lu 177 or Radium 223 can cure Prostate cancer which has spreaded to the bones. And also are Lu 177 and Radium 223 same or different

Jump to this post

I posted this in 2024 This too is valuable

What is Better: Actinium 225, Radium 223 or Lutetium 177?
https://airomedical.com/blogs/treatment-guides/what-is-better-actinium-radium-or-lutetium-for-prostate-cancer

REPLY
melcanada | @melcanada | 2 days ago

8 years 80 now and feel great see my other posts
Had spot rad to L 4 in 2020 then Xtandi, Radium 223 and now Abiraterone with Prednisone Had 2 chemo's but lungs filled with fluid On Oxygen and Prednisone for six months Have now POC Portable Oxygen Compressor for walking and ACER Rollator from Sweden

I posted this in 2024 This too is valuable
https://airomedical.com/blogs/treatment-guides/what-is-better-actinium-radium-or-lutetium-for-prostate-cancer

REPLY
melcanada | @melcanada | 2 days ago

I go to CVH radiation today Wednesday 9:45 to look at spot radiation of my bone in my back left shoulder Its called palliative radiation to stop the pain as I can't sleep without lots of Tylenol and other
With PSA not going down and with PSMA PET Scan proof last month, I qualify for LU 177 Pluvicto but in 2026 at CVH else PMH downtown I had six injections of Radium 223 at CVH a year ago
This is a good read What is Better: Actinium 225, Radium 223 or Lutetium 177?

Thanks for copying most of this and posting copy @northoftheborder
I posted this in 2024 This too is valuable
https://airomedical.com/blogs/treatment-guides/what-is-better-actinium-radium-or-lutetium-for-prostate-cancer

REPLY
melcanada | @melcanada | 2 days ago
In reply to @amee "Can lu 177 or Radium 223 can cure Prostate cancer which has spreaded to the bones...." + (show)
@amee

Can lu 177 or Radium 223 can cure Prostate cancer which has spreaded to the bones. And also are Lu 177 and Radium 223 same or different

Jump to this post

Nothing can cure mets to the bones, just control it Kill of many calls but it hands around
Radium 225 is similar but different LU has radium from Nuclear plant and formulated a few days before the injection That is why one must not miss appointment
I posted this in 2024 This too is valuable
https://airomedical.com/blogs/treatment-guides/what-is-better-actinium-radium-or-lutetium-for-prostate-cancer

REPLY
1 reply
amee | @amee | 2 days ago
In reply to @melcanada "Lutetium-177 PSMA therapy is based on the notion that Lu-177 can stick to the surface of..." + (show)
@melcanada

Lutetium-177 PSMA therapy is based on the notion that Lu-177 can stick to the surface of the cell membranes that make PSMA. Lutathera and Pluvicto, two drugs with lutetium, were the first to get FDA approval. Radiologists can use it if the tumor has spread to other body parts and isn't responding to chemo or hormone therapy.
Radium-223 dichloride, Xofigo, is used to treat advanced prostate cancer metastasizing to the bones. Radium's structure is also similar to that of Calcium, which is the main element in bone tissue. This similarity makes it easier for Ra-223 to get into bone metastases and kill cancer cells. Since there are no cancerous cells in the internal organs, this radioligand is given.
Actinium-225 PSMA therapy is a novel radioligand-based approach to treating cancerous tumors. The medication molecule can bind to the protein in the same way that Lutetium can. It is used in place of Lutathera in cases where the latter medication is ineffective against prostate cancer.

Jump to this post

Can lu 177 or Radium 223 can cure Prostate cancer which has spreaded to the bones. And also are Lu 177 and Radium 223 same or different

REPLY
2 replies
reets70 | @reets70 | 3 days ago

My husband had a prostatectomy in 1993, that’s thirty years ago, and he’s very much alive! After many years of treatment and a very active lifestyle, he is now endstage. At the age of 88, there have been many days that he regretted having the surgery, but for most of this time, life treated us well! Five grandchildren and three great granchildren that he never would have known has made all of the treatments worth it!

REPLY
darryl58 | @darryl58 | 4 days ago

Very encouraging to hear. I have similar numbers and was diagnosed last August. My PSA numbers are now negligible. I'm having pain and weakness in my back arms and weakness iny hands. I don't know if this is side effects from Darolutamide.

REPLY
melcanada | @melcanada | Feb 3, 2024
In reply to @jkwerner "My husband is 74 years old. He has gone through many treatments that eventually stopped working...." + (show)
@jkwerner

My husband is 74 years old. He has gone through many treatments that eventually stopped working. He remained on Lupron injections every 3 months consistently. He was first on dexamethasone 2 and 1/2 years, zytiga for 3 years, These were the more stable years and lower PSA levels. He had testosterone injections for a year that brought his PSA down and then stopped working. Re-tried zytiga last year but it failed. Because of the Pluvicto not being approved in the US until 2021 he waited without any treatment for 9 months. Then to have Medicare approval to try Pluvicto he had to go on chemotherapy drugs. He lost extensive weight and became very weak. This may have been the reason that when he was approved for Pluvicto he was in a weakened state and never really seemed to benefit from this treatment. I think it is going to be a life saver for many men.

Jump to this post

This too is valuable
https://airomedical.com/blogs/treatment-guides/what-is-better-actinium-radium-or-lutetium-for-prostate-cancer

REPLY
View MoreView Less
Please sign in or register to post a reply.