Stage 4 metastasis prostate cancer: Anyone had Lupron shots?

Posted by baxterlee77 @baxterlee77, Mar 27, 2023

Have any of your men used Lupron shots?

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

@jdawkins

My husband is on Lupron. Are you saying the Eligard has less fatigue? I would love to know of any ADT that has less fatigue. I assumed the fatigue was from low testosterone.

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Oh no . Both Lupron and Eligard cause fatigue. Cannot say it is less with Eligard. I just had a very unpleasant reaction to Lupron.

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@cesar52

Yes. T levels too low I believe. I have been off treatment for 7 months now and T levels have been 20 and 21 and PSA has remained undetectable. I was told it would take longer for my T levels to go up because of the fact I was on ADT for so long. My gynecomastia is improved. It was so dramatic at one point that I did not even want my wife to see me without a shirt.

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Did this develop during treatment or after you stopped? I’m sure your wife is just happy you are doing so well.

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During treatment. Yes my wife is happy. I had a good conversation with her after the diagnosis so she knew what to expect. It has helped we have been married for more than 40 years. I got hit with everything: surgery that failed to cure me. Radiation therapy, ADT and Xtandi. But despite being a stage 4A patient I have been blessed. Your spouse has to be on board and be supportive. Otherwise it is extremely challenging to move forward. You cannot fight this disease alone.

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I’m stage four metatastic,hormone therapy,radiation,chemotherapy,now on Xofigo ,agreesive cancer still growing might be getting radiation got one more Xofigo injection not sure what’s next I hate not knowing I’m worried back on chemo !!!

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@melcanada

In patients with serum testosterone castrate levels, hormone-refractory prostate cancer is defined as 2-3 consecutive rises in prostate-specific antigen (PSA) levels obtained at intervals of greater than 2 weeks and/or documented disease progression based on findings from CT scan and/or bone scan, bone pain, or ...Aug 9, 2022 COPY

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I think I understand that and, yes, it sounds like my experience. My PSA jumped (up to 13 or so) about a year and a half ago. That started a series of scans and biopsies.

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I am on Zolodex plus they added Xtandi / Enzalutamide PSA dropped from 9.8 to 4 in 6 weeks Test on 10th if April again

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@kchris5174

This group is quite helpful and helps me to connect the dots. I never thought of the medications as being to blame for the fact that I can no longer do my chin-up routine. I tended to blame my age (82) and a shoulder injury which caused me to lay off. However, my brother went through a 2 year course for his prostate cancer and he complained about a loss of energy so it starts to make sense. Thanks to Mayo for hosting this group, which I look at as a support group.

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To everyone What is the life expectance on all these drugs were taking

Anyone 5 years plus then what

78 on Xtandi for spinal MCRPC this January Zolodex 2 years again

Radiated L2 2 years ago Prostate 5 years ago Want to go 10 more Feel great

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Yes. I recieved Lupron in Oct. of 2018. My PSA readings have been consistently low ever since, at 0.01.
I initially had hot flashes, but not for long. I haven't felt any side effects since. I test every three months. I'm able to exercise. I feel very lucky so far. I try to live in the moment. My positive thoughts go out to all of you.

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@melcanada

To everyone What is the life expectance on all these drugs were taking

Anyone 5 years plus then what

78 on Xtandi for spinal MCRPC this January Zolodex 2 years again

Radiated L2 2 years ago Prostate 5 years ago Want to go 10 more Feel great

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I believe that the paperwork that came along with my Abiraterone said the median life expectancy was 40 months although I’m also taking Eligard so that might alter that data. At any rate I’m doing everything possible to put myself into the upper median.group.

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On Xtandi my medical oncologists said look for 5 years plus The recent release said 67% get 5 yrs

It's in my L2 which was nuked and now my L1 and some in T1 and T11 but slowing

PSA dropped from 9.8 to 4.0 in 6 weeks Next blood test this Monday Prayers..... I feel great

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