Stage 2 Trials of Pirenzepine for Neuropathy

Please share how you got the Pirenzepine....otherwise it is a teaser for those of us who would like relief. Thank you. I am grateful every day for this site and the sharing of information.

Results of the 2a study just published in one of the Lancet group publications. Jan 2026. Generally promising results.
eBioMedicine Home

Advanced search
ARTICLESVolume 123106055January 2026Open Access
Download Full Issue
Topical application of the antimuscarinic pirenzepine increased lower limb nerve fibre density in a phase 2a study in type 2 patients with diabetes with peripheral neuropathy
Ajith Sivadasana ∙ Paul Fernyhoughb,c ∙ Nigel A. Calcuttd ∙ Katie E. Frizzid,e ∙ Kimberly Gardnerd ∙ Angela Hansene ∙ et al.

@proteusx - I thought I would share the link to the research article you posted so that other members can find it easier.
-- Topical application of the antimuscarinic pirenzepine increased lower limb nerve fibre density in a phase 2a study in type 2 patients with diabetes with peripheral neuropathy:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00499-2/fulltext

Thanks. And I would like to add that though WinSanTor's studies have focused primarily on diabetic peripheral neuropathy their researchers have indicated that the drug will likely also have benefits in several other forms of PN, including chemotherapy induced PN, though this remains to be demonstrated. At some point I will comment on my personal experience with "scrambler therapy" in Rome last summer and with my ongoing use of red light therapy and carboxy therapy.