Something new in the treatment arsenal?
AstraZeneca reported positive results from a Phase 3 trial for a breast- cancer treatment, sending its American depositary receipts higher.
Shares of AstraZeneca (ticker: AZN) were up 1.7% to $68.16 in morning trading.
The company said the trial showed that the treatment, datopotamab deruxtecan, showed a significant improvement relative to chemotherapy in terms of progression-free survival. Plans to submit the drug for regulatory approval globally are underway.
Progression-free survival “is defined as the time from random assignment in a clinical trial to disease progression or death from any cause,” according to the National Library of Medicine.
Interested in more discussions like this? Go to the Breast Cancer Support Group.
Hi @leeann66
So good to hear from you! Sorry to hear about the eye issues, but good to hear they have a treatment plan for that. Anything with eyes is always concerning. It sounds like you are doing great and still enjoying life other than that. Glad the other side effects are improving. Thanks for the great update. You always have such a positive outlook. You’re one of the miracle stories. Prayers that all goes well with your eye procedures. Please let us know how that goes. Enjoy the rest of your summer. Blessings, Zebra
@leeann66
It has been almost a year since your last post on this thread. You pop into my head periodically. I’ve been wondering how you’re doing and if you’re still on the new med. Can you provide an update? Thanks, Zebra
Hello and thank you so much for thinking of me.
I have continued in the clinical trial, but now have actually have stopped chemo since April 8.
I have responded really well and the cancer has remained stable, NED in all my bones and lymph nodes, and just a small 1 cm density showing in my left breast, which could be the cancer or could be remaining scar tissue.
After 2 1/2 years on chemo, my body was starting show to signs of fatigue, so my doctor recommended stopping chemo to give my body a chance to heal.
My last chemo was April 8. This past week, since my body is now physically in a better condition, I have started Tamoxifen.
He feels confident that the Tamoxifen will keep things stable although he can’t say for how long but he asked me to trust him and let’s give this a chance, so that is what we are doing.
I will have blood work and see him every 6 to 8 weeks and scans every three months, the next one will be in August and follow up appointment with him in September.
I will try to remember to put a note in this feed following that to let you all know How things are going.
While it’s all very exciting to be off treatment, It is also quite scary. Given the fact I was told with my diagnosis I would be in treatment the rest of my life this feels
Like a gift but a scary one, if that makes sense?
I am getting hair and eyebrows and eyelashes for the first time in 2 1/2 years, my eyes that were heavily impacted by the chemo are much less dry and less painful now which I am really enjoying.
So, all things considered, things are really, really good at the moment!
Thanks again for checking in, have a wonderful summer.
Also not sure if I mentioned it, but the chemo Dato DXD was approved for general use in the US January of this year, and by the end of this year should be available to everyone in Canada.
@leeann66
Thank you for the great update. Congratulations on doing so well on this new chemo! You so deserve a break from all of it, but I completely understand your mixed emotions. I hope others have done as well as you have. Great news on the approval of the drug. I’ll look forward to your future updates. Enjoy your summer!!!