Something new in the treatment arsenal?

Hello! Yes I got the results and everything is still stable, no changes meaning no new lesions, cancer not seen in all
The previous places, still
Showing in the lymph nodes but has not changed in size for 6 months. (Initially they shrunk to half the size but have not changed since!). Overall very good news!!!! Thanks for checking in! 😀

Hello! I have one November 27 so will know about a week after that. I am feeling well! Had one cycle
That I felt like I was getting a flu the whole
Time but was just very run down I think as all good now and back to normal. A few exhausted achy days post chemo but otherwise good and living my life! Reach out and remind me after first week of December for scan news! Hope you are well!

Hello! I have one November 27 so will know about a week after that. I am feeling well! Had one cycle
That I felt like I was getting a flu the whole
Time but was just very run down I think as all good now and back to normal. A few exhausted achy days post chemo but otherwise good and living my life! Reach out and remind me after first week of December for scan news! Hope you are well!

Hi @leeann66
Have you had anymore CT scans since this September update? Cancer in the lymph nodes gone? Still feeling okay? Thanks for any update.

Hello, I am in Montreal and I am in Phase 3 of the trial you are talking about.

The trial is called Tropion 01 for HR+ HER2 - (or low). I started Nov 1, 2022.

To qualify you have to be stage 4 and have already tried a few other lines of treatment. I had been on Kisqali, Afinitor, and Xeloda prior to this trial.

When I started the trial, I had a tumour in my left breast, several lymph nodes under my left arm were impacted, and I had Mets in my hips, my lower spine, my sixth rib, one of my vertebrae‘s and my sternum. Currently the only cancer that can be seen on The CT scan is in three of my lymph nodes, which is significantly smaller.

I imagine we will be hearing more talk about this at the San Antonio symposiu

Here is the link to the latest results on this trial.
https://www.astrazeneca.com/media-centre/press-releases/2023/dato-dxd-improved-pfs-in-breast-cancer.html

Hello,

I was diagnosed stage 4 June 2020 with mets to my bones, started on Kisqali and Anastrozole July 13. After 19 months I started to get pain in my breast, similar to when I was diagnosed. I told my oncologist that I thought the cancer was growing again and a scan showed that it was. I switched to Afinitor and Exemastane but had a bad rash and trouble breathing so was taken off after 6 weeks. I was then on Xeloda for 6 months, I didn't have any indication from my body on how it was doing but scans at 3 months then at 6 months showed it wasn't working and the cancer had progressed.

I was without treatment for 7 weeks while my oncologist tried to get me into this trial, and I started in the Tropion 01 trial November 1. Adjusting to side effects was a bit of a journey but now with the right combination of medication for constipation and nausea (which only happened day 4 and 5 post chemo which is every 3 weeks) things are very manageable.

I have no hair anywhere and have fatigue, but I do all the things I need to do around the house, I go to dragon boat practice twice a week, golf once a week, dinners and drinks with my hubby and our friends and weekends are busy with our 4 kids and 2 grandkids. I am not missing out on anything. Yes, I have to rest more and there have been challenges with chemo mouth sores but again, getting the right combination of medications for all side effects is giving me a very good quality of life!!!

Let me know if you have any other questions, happy to share.

Hello,

I was diagnosed stage 4 June 2020 with mets to my bones, started on Kisqali and Anastrozole July 13. After 19 months I started to get pain in my breast, similar to when I was diagnosed. I told my oncologist that I thought the cancer was growing again and a scan showed that it was. I switched to Afinitor and Exemastane but had a bad rash and trouble breathing so was taken off after 6 weeks. I was then on Xeloda for 6 months, I didn't have any indication from my body on how it was doing but scans at 3 months then at 6 months showed it wasn't working and the cancer had progressed.

I was without treatment for 7 weeks while my oncologist tried to get me into this trial, and I started in the Tropion 01 trial November 1. Adjusting to side effects was a bit of a journey but now with the right combination of medication for constipation and nausea (which only happened day 4 and 5 post chemo which is every 3 weeks) things are very manageable.

I have no hair anywhere and have fatigue, but I do all the things I need to do around the house, I go to dragon boat practice twice a week, golf once a week, dinners and drinks with my hubby and our friends and weekends are busy with our 4 kids and 2 grandkids. I am not missing out on anything. Yes, I have to rest more and there have been challenges with chemo mouth sores but again, getting the right combination of medications for all side effects is giving me a very good quality of life!!!

Let me know if you have any other questions, happy to share.