Something new in the treatment arsenal?
AstraZeneca reported positive results from a Phase 3 trial for a breast- cancer treatment, sending its American depositary receipts higher.
Shares of AstraZeneca (ticker: AZN) were up 1.7% to $68.16 in morning trading.
The company said the trial showed that the treatment, datopotamab deruxtecan, showed a significant improvement relative to chemotherapy in terms of progression-free survival. Plans to submit the drug for regulatory approval globally are underway.
Progression-free survival “is defined as the time from random assignment in a clinical trial to disease progression or death from any cause,” according to the National Library of Medicine.
Interested in more discussions like this? Go to the Breast Cancer Support Group.
So far no nausea ( day 3) no mouth and foot syndrome?
Thank you for your suggestions 😊 I really appreciate it. 🙏🏼🙏🏼
I had nausea every day. Would start just after lunch and end just before dinner. never bad enough to make me vomit, but just enough to feel a bit yucky. Meds sometimes helped, but sometimes not. I also had Some fatigue, but that was pretty much it.
Hi, I use Biotene toothpaste to help with dry mouth, alternate through the day with Magic Mouthwash and Dexamethasone Elixor and for stubborn or more painful sores I use Zilactin-B. It hurts for a few seconds when I put it on, but then it numbs the area providing a few hours without pain, and it also protects it and encourages it to heal. Biotene also has a gel that I sometimes use to help with the dryness in my mouth, but if it’s all full of sores, I don’t bother with that and just frequently use the other meds I mentioned and am extremely careful in what I eat and drink!
I just started Xeloda on Monday ( 3 days). What were your major side effects? I will be on this for 33 treatment days M-F along with Proton Therapy ( double whammy)
What did you use for your mouth sores? Besides magic mouthwash? Hope you are doing well 🙏🏼
Is this treatment for TNBC?
Epigenetic reprogramming? Doesn’t sound like something that could happen in most oncologists’ offices.
HI, Was just put on Xgeva. I am still having a lot of pain in my fractured rib/ lesion area. But thinking it is the fracture and maybe not the cancer causing the pain.. I hope!
Hello, the progressions were all in the same place they had previously been. When I was first diagnosed, I had lesions in the bones in seven places as well as lymph nodes and breast. On my first line of treatment I was NED maybe 16 months, and then disease progressed again, but in all of the same places, no new places.