Signatera Test. Is it truly helpful and worthwhile?

Posted by pbnew @pbnew, Nov 30, 2023

I haven’t met anyone who has used this test. Do oncologists recommend it? How does it help?

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@casbc

I just had my 1st test in October and it IS WORTH IT. They request a tissue sample from the hospital and they keep it on file to compare every 4 months to be sure if there is any cell movement.
My Dr. in Texas at MD Anderson (I live in Florida) uses it to monitor. It supposedly can see up to a year in advance any metastasizing .

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Hi and thx for sharing! May I ask what stage you are? My MO is at Dana Farber and again said the Signatera is not "standard of care" - I have Invasive Lobular Breast Cancer which is often not picked up on mammograms - I got lucky - lumpectomy and radiation and letrozole now for 5-10 yrs. I wish I had asked for a baseline after surgery via Signatera but now that more data is out there I don't understand why so many oncologists won't help their patients - I understand insurance is a big component but some of us would like the information to minimize the constant anxiety of a reoccurrence. In the USA Medicare covers if stage 2 - I am technically stage 1, but grade 2 therefore just curious what stage you are - much appreciated. xo

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@semurrey

Hi and thx for sharing! May I ask what stage you are? My MO is at Dana Farber and again said the Signatera is not "standard of care" - I have Invasive Lobular Breast Cancer which is often not picked up on mammograms - I got lucky - lumpectomy and radiation and letrozole now for 5-10 yrs. I wish I had asked for a baseline after surgery via Signatera but now that more data is out there I don't understand why so many oncologists won't help their patients - I understand insurance is a big component but some of us would like the information to minimize the constant anxiety of a reoccurrence. In the USA Medicare covers if stage 2 - I am technically stage 1, but grade 2 therefore just curious what stage you are - much appreciated. xo

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I'm Stage 4 Metastatic BC. all within a year. The Doctor At MD Anderson ONLY uses Signaterra and not Tumor Markers to determine if the Cancer is on the move or not. I think it's well worth a simple blood test.

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