Signatera results: Does the increase mean cancer is back?

Posted by varg4258 @varg4258, Nov 13, 2023

Signatera Test was done after rectal cancer surgery. May & July test 0.00 MTM/ML and Nov 2023 test 0.05 MTM/ML(positive below Analytical Range).

Does the November Positive 0.05 result mean my cancer is coming back? CT scan for chest/abdomen/pelvis scheduled for end of November this year. Please share your thoughts.

Interested in more discussions like this? Go to the Colorectal Cancer Support Group.

I am in the same place, and waiting for the results on my 3rd test done Saturday.
I learned you can have a Signatera medical person call you and answer any questions you may have.
650-446-4657
Good luck😘

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@cjay

I am in the same place, and waiting for the results on my 3rd test done Saturday.
I learned you can have a Signatera medical person call you and answer any questions you may have.
650-446-4657
Good luck😘

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Good suggestion, @cjay. Were they helpful answering your questions at Signatera?

@varg4258, I can understand that this increase is causing you concern. But more testing is needed to see why. The CT scan is the next step. I know waiting until the end of month must seem like an eternity. How are you doing? How do you keep your mind calm?

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Last year I was diagnosed with small bowel cancer. Surgery removed it and chemo was completed after 6 months in March. The reported MTM/ml after chemo was 2.79 that same month. The following test 3 months later 22.61. I am concerned in the 10 fold increase in such a short time. What does this mean?

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