What experience has anyone had with the Signatera blood test?

Posted by babab @babab, Aug 19, 2024

What experience has anyone had with the Signatera blood test. My results have been 0.13, 0.15, and now 0.17.

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I had Stage 2, aggressive, muscle invasive bladder cancer diagnosed in April 2023. I had 12 weeks of chemo, Radical Cystectomy, and one year of immunotherapy. My Natera has stayed steady at around 0.17 molecules/ml. My oncologist wishes it was down to zero, so I continue having a Natera blood test every four months and also a CT scan. My oncologist says the Natera test is so new that oncologists are still learning how to use it. If you don't mind answering, what Natera numbers are your mother getting and how is her treatment being adjusted?

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@neurodoc 8'2 sevral yrs ago now 0 X 4 times

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That is common across most larger organizations. Natera has opportunities in upgrading and integrating systems/processes. But so do many.

I still have trouble getting up and walking. Plus fatigue in my arms. And a rash that is there but not there. If I scratch it there is a lingering deep pain afterwards for a few seconds. Very strange.

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The text message and email arrived yesterday. I usually find CS friendly but limited as they are not the lab.

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@jaxfl Absolutely. They can only tell you what they see in their system. Going any further to get information, they seem to get very little cooperation from other departments.

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The text message and email arrived yesterday. I usually find CS friendly but limited as they are not the lab.

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For the first time ever Natera sent me a results email with the PDF attached this morning. They did not send a SMS or results available in the portal email like they did previously.

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@jaxfl Natera is not known for customer service. I have only had two rounds so far. They requested the second blood draw before the first results were in. I have only received SMS messages for results. The fact that you actually received an email from them is amazing. I did the same as you with my second test. I started checking the portal around the time they said the results would be available. The text message came three days later to inform me that the results were available.

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For the first time ever Natera sent me a results email with the PDF attached this morning. They did not send a SMS or results available in the portal email like they did previously.

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Congratulations! Great news!

Yes: Natera usually has a considerable lag between results published on the portal and notifications to patients. That is why I check daily and sometimes multiple times daily.

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@eustacia55 Thanks! Taking the good with the bad.

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@jaxfl congratulations! By the way I noticed something this round with Natera. I logged in to my account with them 7 days after my blood draw and could see the result. I didn’t get a text that the result was available to view online until day 9. In the past both were happening at day 7.
Happy to say it is still non detectable, kind of expected as both pet scan and MRI were good.

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@jaxfl Wonderful news! Hope the aches subside soon.

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@eustacia55 Thanks! Taking the good with the bad.

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10/23 signatera was negative.

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@jaxfl Wonderful news! Hope the aches subside soon.

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