How long did you have side effects from Tagrisso?

Posted by sierranevadagal395 @sierranevadagal395, May 12 2:31pm

I've been taking Tagrisso since mid-March after my partial lobectomy in February. Thankfully, the cancer was Stage 1B so no chemo or radiation... just the Tagrisso.

For those of you who take Tagrisso, how long did you experience side effects? Diarrhea is the most unpleasant side effect and hope that I won't have to take Imodium for the duration of my treatment.

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Colleen Young, Connect Director | @colleenyoung | 4 hours ago

In reply to @soldieron "@soldieron ***4oz Kefir*** Sorry" + (show)

@soldieron, I corrected your post above. 🙂

Lisa, Volunteer Mentor | @lls8000 | 5 hours ago

In reply to @soldieron "@lls8000 Sorry for the late reply. Yes, I am drinking water but probably not as much..." + (show)

@soldieron , wishing you well! I’m probably not the best person to give advice on the constipation struggles, as after five years I still don’t have it figured out. I’ll try the kefir.
Start slow at the gym. Moving will only help. I find that it’s helpful for my mental health too.

sierranevadagal395 | @sierranevadagal395 | 1 day ago

Thank you all for your suggestions and support. Kefir is helping!
Update: after nearly 9 months on the 80mg Tagrisso, in addition to the diarrhea I developed a full body rash (very itchy) and my fingernails became quite brittle and seemed to stop growing. I shared these new symptoms with my oncologist and he agreed to drop the dosage to 40mg. Thankful - and hopeful that this will ease the side effects.

I was diagnosed Stage 1B adenocarcinoma in January 2025 and had my partial lobectomy (with a robot assist!) in February 2025. As many have said, this is a journey ....

soldieron | @soldieron | 1 day ago

In reply to @soldieron "@rlf66 Sorry for responding so late. Been very busy. I drink 4oz of Kefir in the..." + (show)

@soldieron
***4oz Kefir***
Sorry

soldieron | @soldieron | 1 day ago

How many mg are you prescribed? Also, how long will you be taking it? I have to take it for three years.

soldieron | @soldieron | 1 day ago

In reply to @lls8000 "@soldieron, These medications can certainly wreak havoc on our GI systems. I take a different targeted..." + (show)

@lls8000
Sorry for the late reply.
Yes, I am drinking water but probably not as much as I should. I haven't tried to go for walks yet, but will the next week. I just joined a gym and will combine it with the walking. I will try to find some adult pull up panties as I don't want an accident while walking.

soldieron | @soldieron | 1 day ago

In reply to @rlf66 "@soldieron Thanks so much for sharing. How much Keifer do u drink per day?? blessings to..." + (show)

@rlf66

Sorry for responding so late. Been very busy.
I drink 4oz of Kefir in the morning. I will say it is an 'acquired taste.' It's like liquid yogurt only a lot more tangy.

Lisa, Volunteer Mentor | @lls8000 | Dec 1 10:09pm

In reply to @soldieron "I began Tagrisso 80mg on August 1. Normal for the first week. After that the diarrhea..." + (show)

@soldieron, These medications can certainly wreak havoc on our GI systems. I take a different targeted therapy and have struggled too. It can take a while for our bodies to adjust. Hopefully you figure out what works for you. Are you drinking a lot of water? Are you able to go for regular walks?, moving can help.