Seeking Wisdom and Guidance

Posted by jbuscher123 @jbuscher123, Dec 30, 2025

I will admit this is a group I had not been planning to join as a fit, 59-year old, but here we are. I have been reading various posts to become more educated about prostate cancer but thought I'd seek out the collective wisdom and fortitude of those here.

This past November, during routine annual bloodwork, my PSA level was "abnormal" at 5.8. Thinking it was an aberration, I asked for another test three weeks later, only to find the PSA level had risen to 6.5. The PSA "free" number is 10.3, which I also have read is not great for signaling whether I likely have prostate cancer or not. I am alarmed and terrified, as most of you who first receive these numbers must feel too.

I am under good care right now at Johns Hopkins urology, with the doctor who helped eradicate low-grade bladder cancer 9 years ago with no recurrence thus far. I also have survived surgical removal of malignant melanoma detected back in 2005.

I decided to open an account with the Mayo Clinic as backup and for second opinions, if needed.

While my next step is an MRI of my pelvic region January 7th, however I found it concerning that my doctor immediately suggested a biopsy, even before seeing any results from an MRI, based on the dramatic increase in PSA number Is that unusual? I was fighting the weird flu bug that is going around during my second PSA test and was on amoxicillin, so wondering if that may have affected my score?

The biopsy is scheduled for late January, leaving me wondering what to do in the meantime except fret, be anxious and lose sleep. Each day, I can only think about a cancer growing inside of me with nothing being done. I won't even know the results of the biopsy until mid-February. That will be over six weeks of just sitting around thinking about worst case scenarios.

I realize no one here is a doctor or can provide advice especially without knowing the results of an MRI or biopsy. My only source of information is what I read on the internet, and that can lead me down rat-holes that I'd rather not enter. I have read on here and other place that testosterone can lead to cancer spread. Is there anything I can do about that in the meantime? I still lift weights, which can produce testosterone. Should I quit? Don't I need strength for a potential battle with cancer?

My sister just passed away December 24th from metastatic breast cancer, which make me wonder if I need to be tested for a genetic disorder that makes it more difficult to fight cancer. My father had a prostatectomy 25 years ago at age 70, and he is still around at 95 in pretty good shape.

As you can tell, I'm a little lost and confused. So thought I would post here and seek advice on how to handle this interim period, while simultaneously entering a chat with those who have experienced MUCH more than me thus far. I am grateful for any advice or wisdom.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Profile picture for pesquallie @pesquallie

@kujhawk1978

DRE did not detect my cancer and my family doctor said I had a large prostate while the NPR said I had the prostate of a teenager while the biopsy also said I had a very small prostate.

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@pesquallie Same here - seems the tip of the index finger is not the best judge of pathology.
Although it’s been the mainstay of diagnosis for decades, newer tests ( blood, urine) will probably render it obsolete in a few years…
And that’s a good thing since SO MANY men avoid screening because it involves a stranger sticking his/her finger up your ass…talk about invasion??

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Profile picture for jeff Marchi @jeffmarc

Your timing for the MRI and biopsy is so soon that it really isn’t an issue. Prostate cancer is relatively slow growing and your being sick could’ve affected your PSA. Your doctor was getting a little anxious Considering how quickly you can get an MRI.

You should definitely get genetic testing. I got PC at 62 because I have BRCA2. My brother got it at 77 because he didn’t, but he had a father with PC. My father died of it at 88 but he did not have BRCA. I got it from my mothers side of the family. Both of her sisters had breast cancer. One died of it and So did her daughter at 60. My mother never got it, but passed on the BRCA2 to me.

Has hereditary genetic testing been offered to you by a doctor? You can get it done free with the below link, if you live in the United States. Do not check the box that you want your doctor involved or they won’t send you the kit until they get in contact with your doctor. It takes about three weeks to get the results and then a genetic counselor will call you.
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http://prostatecancerpromise.org/

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@jeffmarc do you have to have PC to get this free test

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I went to the ER with having a hard time urinating and frequent time especially at night. They thought a UTI. After 4 days I felt I was getting worse and went to another doctor. He add Flomax and change antibiotics to Cipro. I saw urology 5 days later but had my PSA done on my own before seeing him and and it came back at 50. (Back in August for my physical it was .85) Around the beginning of Dec. The urologist said sounds like prostatitis and follow up just in 2 weeks and we will retest your PSA then. It was 12 and now he's just saying follow up in 2 months. I retested my PSA again on my own and it was 8 on Monday. The wait is stressing me out to just wait and see how low my PSA will go they decide to check for cancer. My urine test showed UTI they say but it does show white blood cells as signalling and infection. I stressing and seem to have inflammation and last night some pelvic pain. It make me thing the cancer is spreading why they just stand by and wait.

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Profile picture for lavonzell @lavonzell

@jeffmarc do you have to have PC to get this free test

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@lavonzell
Yes. It is a study of prostate cancer patients

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Profile picture for lavonzell @lavonzell

I went to the ER with having a hard time urinating and frequent time especially at night. They thought a UTI. After 4 days I felt I was getting worse and went to another doctor. He add Flomax and change antibiotics to Cipro. I saw urology 5 days later but had my PSA done on my own before seeing him and and it came back at 50. (Back in August for my physical it was .85) Around the beginning of Dec. The urologist said sounds like prostatitis and follow up just in 2 weeks and we will retest your PSA then. It was 12 and now he's just saying follow up in 2 months. I retested my PSA again on my own and it was 8 on Monday. The wait is stressing me out to just wait and see how low my PSA will go they decide to check for cancer. My urine test showed UTI they say but it does show white blood cells as signalling and infection. I stressing and seem to have inflammation and last night some pelvic pain. It make me thing the cancer is spreading why they just stand by and wait.

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@lavonzell
BPH and a large prostate can really screw up people because the PSA number is just way too high, but it’s not prostate cancer, Usually.

Had a friend Who’s prostate was huge and his PSA was always around 50, Had multiple biopsies they never found anything.

It sounds like your case is one that needs to be monitored.

If you are really paranoid about having prostate cancer, you could get a PSE test, which would Definitively tell you whether or not there was cancer in your system and you needed a biopsy.

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