Root Canal on Prolia

Posted by sbt54 @sbt54, May 18 7:37am

I just got my 1st Prolia shot last week and now I need a root canal. Will I be ok?

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Hi @sbt54. There shouldn’t be any reason to delay your root canal treatment with having just one shot of Prolia. RCT is limited to the nerve canals of your tooth and doesn’t require any direct oral surgery impacting the bone.

There’s only a very rare possibility for some patients receiving bone loss treatments to develop osteonecrosis after an extraction, oral surgery or implants. The risk elevates with higher, long term dosages of the medication. Example; Patients who receive chemotherapy and experience severe bone loss are placed on higher dosages. You’ve just begun receiving Prolia and the benefits greatly outweigh any risks. ☺️

I spent a great portion of my career as a dental assistant, assisting with RCT and oral surgery. Do you have any questions about your root canal?


TY so much for your input. I feel more at ease now.


Quite some time ago I had a root canal in a molar. About 6 months ago, I discovered a bubble on my gum and had painful swelling in my jaw. Fearing the worst, I made an appointment with an endodontist and a periodontist;
based on x-rays and CT’s, they recommended an extraction. I stopped short of agreeing to the extraction because of Reclast, Tymlos and now Evenity and the whole ONJ issue, which terrifies me!

I had a consult with a second endodontist who gave me better than 50/50 odds that he could repair the original root canal - which I had done about six weeks ago - to avoid the extraction. It’ll be a wait and see for the next 4-5 months to make sure the repair worked, and I am hopeful.

Any dental procedure that disturbs the jawbone should be avoided if at all possible. I kept my rheumatologist in the loop to make sure he knew what was going on in the off chance I had issues with any dental procedures (including root canals) that could possibly result in an emergency. I am also very careful to make sure any dental professionals know that I am on bone-building meds and that I am aware of ONJ in patients using the aforementioned treatments.

I am very appreciative of the endo who was willing to try a root canal instead of pulling the tooth. Wishing you all the type of endodontist who will “give it a go”. Cheers!

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