Results of RALP pathology report

Posted by sicescu2 @sicescu2, Jun 27 1:17pm

77 year old, athletic, otherwise healthy. Procedure was done 6/6 and question. Gleason 4+3, cribriform found. Perineural Invasion, EPE Present, Focal in neurovascular bundle. pT3a. High Grade neoplasia. Not in lymph nodes.

Is this Stage 3 cancer? Waiting for first PSA result in July. I am having difficulty translating all of this. Thanks.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

mlabus3 | @mlabus3 | Jul 5 12:25pm

In reply to @jeffmarc "A surgeon does surgery, Once it’s done, and you have no more urological issues you need..." + (show)

i am looking for a RO that is familiar with all the radiation and hormone tools and tricks. I just dont think a lot of them have that much experience in more advanced cases. I have had a prostatectomy on 6/18, and shows IDC and cribiform large/basal. I had and EPE and PNI but negative margins. Although hopeful, I think it is just a matter of time before I get a recurrence, and want to be prepared with plan A, B and C. Any recommentions with knowledgeable and experienced ROs would be appreciated. Ill go anywhere, but COE is mandatory.

jeff Marchi | @jeffmarc | Jul 5 1:58pm

To: @mlabus3 asking for RO recommendations

Did you get a decipher test? It will tell you how likely reoccurrence is possible. Cribriform frequently causes the test to be on the high side.

What was your Gleason Score, that tells a lot.

Dr. Roach at UCSF is an extremely experienced RO.

Others may know some doctors close to you if you mention what state you live in.

Large Cribriform is pretty aggressive, It can increase the risk of occurrence by 16 times. Your having basal cells means it is usually less aggressive according to some studies.

In summary, if you are diagnosed with prostate cancer involving a large cribriform pattern, particularly the invasive type (without basal cells), it is considered an aggressive feature and should be carefully discussed with your doctor to determine the appropriate treatment approach.

For more information, you could do a search like this

“how aggressive is cribiform large/basal”