Has anyone had SBRT after prostate cancer recurrence post IMRT?

Posted by kuz @kuz, Jun 28, 2023

Has anyone had SBRT after a recurrence post Imrt.
I am 79 had radiation 16 years ago and now I have to tackle the beast again.
Thanks

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I had a radical prostatectomy and then radiation 7 years later, for a recurrence. I was in remission for 2 years after that, and now I’m on my 2 nd recurrence. Watching and waiting for next treatment 😬😬😬

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What i sthe plan

Me too at 78 back on Zolodex Then 2 ys later Xtandia nd Xgeva

Rad my L1 lumbar Now in L2

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What is the average effectiveness of Enzalutamide or Xtanda? Anyone on it for 3 or more years? What is next if it stops?

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With MRIdian SBRT post prior treatment is available due to reduced margins and gating. Consider consult with Dr. Kishan UCLA, Dr Rod Ellis Genesis Care in Ft Myers and Dr. Himanshu Nagar, Cornell.

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RP Biopsy clean
1time PSA zero
90 day recurrence
39 rad tx
Eligard 9 months @present
PSA 0.024

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@melcanada

What is the average effectiveness of Enzalutamide or Xtanda? Anyone on it for 3 or more years? What is next if it stops?

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I took Xtandi for 26 months. I did great but after 9 months off it, my PSA went from undetectable to 1.1. A PSMA PET SCAN showed the reason: a 9 mm paraortic lymph node. I was in remission for 4 years. Getting spot radiation next week. 5 sessions only. We got to be resilient. PC will not leave you alone. At least in my case. Xtandi is a great drug.

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I should say after 9 months OFF IT.

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@cesar52

I took Xtandi for 26 months. I did great but after 9 months off it, my PSA went from undetectable to 1.1. A PSMA PET SCAN showed the reason: a 9 mm paraortic lymph node. I was in remission for 4 years. Getting spot radiation next week. 5 sessions only. We got to be resilient. PC will not leave you alone. At least in my case. Xtandi is a great drug.

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My psa went down from 9.8 to 1.7 in 2 Mos
Now 2.3 in next 3 months Is that a concern

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Yes. It could be. Every time the PSA goes up it may signal spread . The good news is that is unlikely to be due to bone Mets with a PSA that low. A PSMA PET SCAN is needed. It detects small metastatic lesions better than other tests. Or your doctor may repeat PSA to see it keeps rising. Best to you. Stay strong.

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@cesar52

Yes. It could be. Every time the PSA goes up it may signal spread . The good news is that is unlikely to be due to bone Mets with a PSA that low. A PSMA PET SCAN is needed. It detects small metastatic lesions better than other tests. Or your doctor may repeat PSA to see it keeps rising. Best to you. Stay strong.

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Thank you for your help.
Hoping to start salvage SBRT next month.

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