Reclast infusion long term side effects
Hello,
I’m new to this forum.
I had a Reclast Infusion in May 2025. After a year dealing with knee pain issues my Dexa Scan results were terrible.
My endocrinologist had already suggested I’d need it, after doing some research I refused it for about 5 years.
Since the infusion, I’ve had digestive problems and pain on my left ribs. Strangely, on the first 24 hours after the infusion this is the exact place where I had intense sharp pain. It’s mostly during the night and in the morning.
Anyone experiencing the same?
Thank you!
Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.
Connect

dannyandebbie, thank you, again. I'd wondered if the steroid wouldn't have to be given early in the adverse response. What was the timing of the steroid for you. Was it difficult to obtain. Are your kidneys involved.
No doubt your willingness to tell us about your experience with Reclast has saved some a similar reaction.
To hear the long term consequences is sad, and provides caution. There have been many lawsuits against Novartis because of this drug. I pray you get resolution of this long lasting pain.
We are supposed to be able to trust our doctors. Many of them actively discourage any patient research, laughing at the google "rabbit hole." Some doctors encourage research even providing links to reliable research. We tend to trust our doctors, tolerate side effects and then blame ourselves.
I hope you keep posting. It is unusual to hear long term effects. Your generosity is deeply appreciated.
-
Like -
Helpful -
Hug
1 Reaction@lollyb I always get the fluid bag first! No problem for me. I just had my second infusion last week,
-
Like -
Helpful -
Hug
4 ReactionsI had heartburn, hip, back pain in my bones for a year after my Reclast infusion. After a year the ache and pain went away. I took all the precautions suggested before an infusion. This pain came on a month or so after the infusion. No, I haven't’ gotten a second infusion.
-
Like -
Helpful -
Hug
5 ReactionsI trusted my doctor and had 3 infusions. Instead of feeling better, I fell the first year and broke 2 ribs on my left side, I thought well the medication had not had time to make a difference.
2 years later, being last summer, I tripped twice, been hospitalized twice, first time broke 3 ribs on my right side, a few months later, fell again broke 2 more ribs on my right side. I am very distraught and now it’s too late. Damage has been done 🥲 I just pray that I don’t break anymore parts of my body
-
Like -
Helpful -
Hug
6 Reactions@kmketter If I may ask, what is your height & weight? I'm very small and thin. I've been prescribed Reclast but the more I learn the more hesitant I become, so I'm trying to get more information before starting. thank you.,Sarah
@shmbrd not sure if you were asking me or KMKetter; I’m a male, 5’2” around 119 weight. 21 months out and continue symptoms from my infusion. My endocrinologist says it is not from the infusion, I say it is….did not have these symptoms ( shoulders and left foot pain, fatigue, nausea and aches and burning in my lower backside). I have Ankolosing spondylitis (50 years) and have had bladder cancer 5 times over the past 16 years. Retirement two years ago and was feeling pretty good until infusion. My endocrinologist say I need additional infusion, Reclast did not cause these symptoms, sent me to rheumatologist, who sent me to neurologist; both had no explanation for my symptoms. I go to physical therapy bi-weekly, helps some….just try to stay positive and as active as I possibly can! Best of luck!
-
Like -
Helpful -
Hug
2 Reactions@dannyandebbie Thanks for taking time to reply. Take good care of yourself, I hope your symptoms will lighten soon.
-
Like -
Helpful -
Hug
4 Reactions@shmbrd seems the more I use my arms or foot the next day I pay for it, hopefully time heals all wounds!
-
Like -
Helpful -
Hug
1 Reaction@daisy17 I had my reclast last Friday. Its been 1 week today.My joint and bone pain has been unbearable. I went to the DR today she blamed the antibiotics I was taking. I came home and looked it up, there is no real interaction with the 2 drugs. I cried like a baby, I can't bend my fingers or close my hands. It also caused me to have an eye ulcer and that is why the antibiotics.
If they would read, it says severe bone pain and muscle pain.
I told my husband we all have to take care of ourself because they don't anymore.
-
Like -
Helpful -
Hug
8 Reactions@penny57
I’m so sorry… this is so recurrent
We need to create a data base of these cases and report it to the FDA or the Drug Company.
I hope you feel better.
-
Like -
Helpful -
Hug
2 Reactions