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Reclast infusion

Posted by eead @eead, May 20, 2025

I had the Reclast infusion at the end of February 2025. Since then I have had great pain in different parts of my body. I have gone from being a very active person (walking, gardening, exercising, etc.) to being unable to do most things. The pain is especially bad at night in my lower extremities, causing me to have difficulty sleeping. The pain management doctor wants me to have a spinal epidural for narrowing of the spinal and foramanal canals because the pain in my back, buttocks, thighs, and legs is so bad. Could the Reclast be causing some of this pain? If so, is there any way to reverse the Reclast?

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jpeach | @jpeach | Apr 10 9:42pm
In reply to @eead "Sorry to hear so many people are experiencing a great deal of pain after having the..." + (show)
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Sorry to hear so many people are experiencing a great deal of pain after having the Reclast infusion. None of the doctors want to address that Reclast could be the problem for so much pain. However, it sure seems to be a coincidence.
Even though I cannot say with certainty that the Reclast is causing the excruciating pain I'm having, after what I am going through I regret having the infusion. I agree that it would have been better to break a bone than to suffer night after night without much sleep, as well as a great deal of pain each and every day.
It's too bad that there is no way to reverse the infusion. I'm hoping that the spinal epidural will help, but have not scheduled an appointment.
Does anyone have experience with spinal epidurals, and what was the outcome?

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@eead
I had a spinal epidural about a month ago for spinal stenosis pain.
It did not do anything and now I have the steroid in my body that will lower your score on a DEXA for 6=12 months. I have heard some people do get relief from them but only for a few months and it is another steroid in your body.

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gravity3 | @gravity3 | Apr 11 5:24am
In reply to @susanphilipson "I have been on Reclast for 5 years, it has been great. Now I have been..." + (show)
Profile picture for susanphilipson @susanphilipson

I have been on Reclast for 5 years, it has been great. Now I have been told that 5 years is the limit for Reclast. I have moved to Prolea but I don’t like it. Any ideas about what I can take?

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@susanphilipson

How many injections of Prolia have you had after 5 years on reclast? Sound like you have not had an anabolic like forteo, tymlos or evenity. What are your dexa scores at this point?

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jchasteen | @jchasteen | 6 days ago
In reply to @susanphilipson "I have been on Reclast for 5 years, it has been great. Now I have been..." + (show)
Profile picture for susanphilipson @susanphilipson

I have been on Reclast for 5 years, it has been great. Now I have been told that 5 years is the limit for Reclast. I have moved to Prolea but I don’t like it. Any ideas about what I can take?

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@susanphilipson
Did an endocrinologist tell you to take Reclast for 5 years?

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loriesco | @loriesco | 5 days ago

The stenosis is probably your problem, which is why the epidural is being recommended. However, it is also possible that your bones really need what the rec class has to offer and the pain you are feeling at night is due to your bones or your bone marrow fabricating what the RECLAST is helping them generate to strengthen your bones. So hang in there and try to see what they can give you for relief. When I go back for my next RECLAST I’m going to have them slow down the infusion give me less of a dose and flush lots of water and Tylenol before I go in for it. Good luck everyone.

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loriesco | @loriesco | 5 days ago
In reply to @jpeach "@eead I had a spinal epidural about a month ago for spinal stenosis pain. It did..." + (show)
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@eead
I had a spinal epidural about a month ago for spinal stenosis pain.
It did not do anything and now I have the steroid in my body that will lower your score on a DEXA for 6=12 months. I have heard some people do get relief from them but only for a few months and it is another steroid in your body.

Jump to this post

@jpeach you do not need to worry that is only for high dose oral steroids. The injected steroids like you had are localized and only if you were repeating them several times a year would there be any concern? Don’t worry it won’t have an impact on your DEXA nor your bone density.

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