Reclast BEWARE causes broken femur!

Posted by missprince @missprince, Feb 14, 2025

Doctor put me on Reclast for 3 years. By third year after iv left leg hurting and getting weaker. Finally, one day leg gave out and I fell to the ground with broken femur. Emergency Surgery. After this several doctors told me it was due to Reclast. Was never told Reclast could do this. Women should avoid this iv. I will post what happened to me wherever I can. To put this drug out knowing it can cause a broken femur is horrible. Women should be told this side effect before receiving the drug. Having a broken femur is a terrible thing with the pain and surgery. I am 3 months out from surgery and still recovering. Now my doctors tell me I should not get anymore reclast! Too late for my broken Femur! Beware of Reclast!

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Profile picture for gravity3 @gravity3

Does he want you to finish prolia after two shots because the rebound issue is not as great? I am looking at a similar position but I am 77 And according to the actuarial tables my lifespan average is 84. So if I stayed on prolia for what might be 7 years i could imagine it although I do have some additional joint pain. What were your dexa numbers after evenity? The prolia was to help retain your gains from evenity. Did he talk to you about prolia rebound. Did you ask him about adrug holiday and if and when in your drug sequencing plan that might be possible.
Do you take hormone replacement? That may be of benefit if their are no health issues that might be risky for you

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Yes to the rebound issue. My Dexa after Evenity went from 2.9 to 1.9 (spine), 2.6 from 2.5 (fem nexk) and 1.8 from 1.9 (total hip. Originally, my doctor and indicated that I could go on a drug holiday after Evenity/Prolia but now she is suggesting that I will lose any gains if I stop meds. I was not offered HRT because I am breast cancer survivor and now its too late (hysterectomy 9 yrs ago). In hindsignht, that would have been a good option.

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Profile picture for gussie @gussie

I am going to be 84 next month and was diagnosed with osteoporosis and osteopenia in my fifties. I saw a endo in San Francisco who specializes in osteoporosis and at that time he didn't like Foxomax so we just did a wait and see. At age 65 I was diagnosed with an immune disorder meaning my immune system doesn't work so I do infusions of other peoples blood plasma to get their antibiodies. When reclast came out he didn't want to put me on that because he didn't know how my crazy immune system would react to it. So all these years I've done nothing except take 2000 units of vitamin D a day. This is something that now I think osteoporosis might be genetic. Three years ago both my daughters in the same year broke bones in their bodies but hadn't been diagnosed until that happened. My daughter in Maryland has it so bad she went on the newest product where she injected herself every night for two years until her insurance stopped covering it. The daughter in LA broke her femur without even doing anything. So both daughter's have it.

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@gussie I am sorry to hear about your daughters. I too have 2 daughters and I have forwarned them about osteoporosis. They are in their late 20s so they are still building bone and have talked to them about calcium, weightlifting, and making sure they have all the necessary minerals to build bone. I wasn’t diagnosed until I turned 63 through a DExA, so I have also told them to start getting tested before (around age 50), during and after menopause.
Incidentally, my grandmother must have had OP. She fractured her wrist in her 80s and she lived until she was 95. My mother tripped and fell last year; she was 90 and she had a total hip replacement. She is very active and still drives. She did tell me recently that she was diagnosed with osteopenia in the 1990s and she decided NOT to go on meds. That is over 25 years ago!

I hope that even though the disease itself is hereditary, I can also learn from my grandmother and mother that they did fine WITHOUT medication and perhaps their bone QUALITY has been handed down to me as well. They both ate very well and were always very active too.

So did you end up taking any meds? How are your tscores now?

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My endocrinologist put my on Reclast infusions. After the second infusion my left femur broke with no warning. I walked about 30 feet and next thing I knew I was on the ground in disbelief.
After surgery and rehab I went to an osteoporosis specialist and he informed me that the breakage most likely was due to Reclast. He put me on Prolia and my bone mass has increased since then. A little jab every 6 months. 2 years ago my Dexascan show 7 percent bone improvement.
I take 600 mg of calcium twice a day and d3 daily.
I am a 76 year old male.

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Profile picture for tfmiller @tfmiller

My endocrinologist put my on Reclast infusions. After the second infusion my left femur broke with no warning. I walked about 30 feet and next thing I knew I was on the ground in disbelief.
After surgery and rehab I went to an osteoporosis specialist and he informed me that the breakage most likely was due to Reclast. He put me on Prolia and my bone mass has increased since then. A little jab every 6 months. 2 years ago my Dexascan show 7 percent bone improvement.
I take 600 mg of calcium twice a day and d3 daily.
I am a 76 year old male.

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@tfmiller

Are you saying that reclast then prolia are your first meds? Has she/he talked to you about anabolics and a drug sequencing plan?

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Profile picture for gravity3 @gravity3

@tfmiller

Are you saying that reclast then prolia are your first meds? Has she/he talked to you about anabolics and a drug sequencing plan?

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@gravity3 No. That’s just how my endocrinologist started me. Prolia is mainly for women but since Reclast failed me I was permitted to start Prolia injections.
I don’t know the odds of breaking a femur with Reclast. Maybe doctors should give the patient the choice of drugs knowing that there’s a chance of broken femurs.
I had to stay in a rehab hospital til I could walk which took me about a month.

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Profile picture for tfmiller @tfmiller

@gravity3 No. That’s just how my endocrinologist started me. Prolia is mainly for women but since Reclast failed me I was permitted to start Prolia injections.
I don’t know the odds of breaking a femur with Reclast. Maybe doctors should give the patient the choice of drugs knowing that there’s a chance of broken femurs.
I had to stay in a rehab hospital til I could walk which took me about a month.

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I read this post because the 'broken femur after that med' caught my attention.

One month in rehab to walk again. That's quite a situation.

You feel better now tho right? The change in med is helping.

That's good news. I hope you've continued
recovering.

Thanks for describing this experience here.

I agree that such info re potential breaking of bones should be presented to someone before they decide to try it. Did you find out any more about how common those odds are?

Hope I'm not asking too many questions. Yikes, what a shock that fall & why must have been.

Seems you've got determination in your personality.

Good on you & all the best.

@tfmiller

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Profile picture for tfmiller @tfmiller

@gravity3 No. That’s just how my endocrinologist started me. Prolia is mainly for women but since Reclast failed me I was permitted to start Prolia injections.
I don’t know the odds of breaking a femur with Reclast. Maybe doctors should give the patient the choice of drugs knowing that there’s a chance of broken femurs.
I had to stay in a rehab hospital til I could walk which took me about a month.

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@tfmiller Hi. Well the surgeon who fixed my leg mentioned that half the people my age who break a femur die within 5 years. So I was determined not to be that person.
The inserted a titanium rod and my leg muscles were cut. After the operation I could not lift my leg at all. It was quite funny to me to look at my leg and say” lift” and nothing happens.
That was 4 years ago. I’ve been on Prolia since then and my Decsa scan showed 7 percent improvement in my legs. My next test is in December. I will share the results then.
I do a lot of walking and hiking and I attribute that to part of the improvement.

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Profile picture for brendammc @brendammc

Could you tell me where you found the prep work information? I definitely want to be prepared.

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@brendammc wow awful this is the first I’ve heard of statins causing fractures.!! which one which statin were you on? I will have to check with my cardiologist before I possibly have a fracture.
76 had osteo for yrs evidently

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Profile picture for mwendt54 @mwendt54

I’m supposed to start Reclast and I’m terrified. I can’t take any oral osteoporosis drugs because I have GERD. Additionally I am terrified of the dentist and haven’t been to the dentist in well over 5 years. I think I should go before taking this medication just to make sure I have nothing wrong where I’d need anything done in my mouth which I read can cause serious problems. I simply don’t know what to do. Any advice would be appreciated.

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@mwendt54 I’d go take care of that dental work ASAP!!!

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Profile picture for tfmiller @tfmiller

@gravity3 No. That’s just how my endocrinologist started me. Prolia is mainly for women but since Reclast failed me I was permitted to start Prolia injections.
I don’t know the odds of breaking a femur with Reclast. Maybe doctors should give the patient the choice of drugs knowing that there’s a chance of broken femurs.
I had to stay in a rehab hospital til I could walk which took me about a month.

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@tfmiller

We all have choices but it is up to each of us to do our own research and be able to discuss treatment plans with our doctors. That is now my approach at 77.

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