Reclast affect on Evenity ?

Posted by 255anny @255anny, Sep 9, 2024

I see my Endo Dr. Wednesday. Hopefully I can resolve this drug issue and move on. I have one question. It has been brought up in our discussions, but I'm wondering if any of you can expand on it a bit further. If I have the 1 infusion of Reclast and the plan is to follow that with 1 yr. of Evenity, do you begin the Evenity 12 months after the Reclast infusion? I seem to remember some mentions that the Reclast is so strong it might blunt the Evenity. If this is so, then would the start of the Evenity be delayed further out than the 12 month mark from the Reclast infusion? Do you need bone markers to measure this?

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

Profile picture for gently @gently

brendammc,
the low bone density would make Evenity a consideration. It adds bone the most quickly and could give you a scaffolding effect protecting you from fracture. Personally I would go straight to Forteo, even so. But think you should give Evenity a thought considering where you've fractured and looking carefully at the accuracy of the -4.5.
Each of these drugs create a different quality of bone
Forteo just creates the best bone, the strongest and most resilient. It is one of the two medications that reconstruct the cartilage structure in the spinal vertebra. Fracture protection begins more quickly than bone density with Forteo use.
Evenity increases bone density the fastest. And it is amazing. The bone lain down is heavier without the communication channels that make integrative bone. It doesn't repair the inner layer of bone, but lays the bone on (against) the outside of existing bone. It's only tempting to me where the bone is likely to fracture very soon.
I wouldn't consider Reclast because it is just too slow. It builds bone by collecting it over time. I like that it protects against further loss, but it can't repair older fissured bone,.
The mechanism of both Reclast and Evenity prevent the repair of bone that I think you need at -4.5.

Another complication with Evenity is what do you take after it, because that bone is lost within a year.
Some few are taking a second year of Evenity. Others are following with Reclast and, of course, Amgen wants you to take Prolia.
Some agile doctors are prescribing Tymlos following Evenity which seems (from individual reports here) to be maintaining the Evenity-bone.
Remember though that I'm just a fellow traveler without the scientific background of our doctors. I hope that the truly wise will contradict me. And hope that you feel free to contact me.
Blessing your choice.

Jump to this post

@gently I had the 7th month of evenity shots today. Started the discussion of what to take next with the nurse practitioner. She said most do rec last or prolia 30 days after last month of evenity, then 2 times/year.
After my January bone density I will have this discussion with dr.
I believe in being involved in the decision and arming with lots of info!

REPLY
Profile picture for barbyb50 @barbyb50

@gently I had the 7th month of evenity shots today. Started the discussion of what to take next with the nurse practitioner. She said most do rec last or prolia 30 days after last month of evenity, then 2 times/year.
After my January bone density I will have this discussion with dr.
I believe in being involved in the decision and arming with lots of info!

Jump to this post

@barbyb50 Can you clarify what you mean by "Most do rec last or prolia 30 days after last month of evenity, then 2 times/year. I am not sure what you mean by that. Thank you, Deborah L

REPLY
Profile picture for deborahla @deborahla

@barbyb50 Can you clarify what you mean by "Most do rec last or prolia 30 days after last month of evenity, then 2 times/year. I am not sure what you mean by that. Thank you, Deborah L

Jump to this post

@deborahla
From what I have read most drs suggest going on reclast or prolia to lock in all of the evenity gains.
Those are one or two times a year as opposed to monthly.
I haven’t research the difference between them.
Once I have the next scan scores and see dr I’ll have more information.
Hope that helps!

REPLY
Profile picture for deborahla @deborahla

@barbyb50 Can you clarify what you mean by "Most do rec last or prolia 30 days after last month of evenity, then 2 times/year. I am not sure what you mean by that. Thank you, Deborah L

Jump to this post

@deborahla
30 days or so after my last evenity injection, i will receive a reclast infusion once. It’s possible i will need Reclast once a year for a year or two or three. The other option, after the Evenity is to take fosomas (alondenate) but I’m choosing the Reclast since I take would rather not have another pill to take.

My bone scan, after a year of evenity is only my right hip is osteoporosis, -2.7 and osteopenia is -2.5. I’m hoping (wondering) if continued weight lifting and the Reclast can keep helping maintain my gains, and even improve on them. The endocrinologist did say Reclast does help a bit in continuing bone building (but not in a big way.).

REPLY
Profile picture for willow5 @willow5

@deborahla
30 days or so after my last evenity injection, i will receive a reclast infusion once. It’s possible i will need Reclast once a year for a year or two or three. The other option, after the Evenity is to take fosomas (alondenate) but I’m choosing the Reclast since I take would rather not have another pill to take.

My bone scan, after a year of evenity is only my right hip is osteoporosis, -2.7 and osteopenia is -2.5. I’m hoping (wondering) if continued weight lifting and the Reclast can keep helping maintain my gains, and even improve on them. The endocrinologist did say Reclast does help a bit in continuing bone building (but not in a big way.).

Jump to this post

@willow5 Thank you for the information. We appear to be on similar paths. I finish Evenity next month, then do a Dexa and see the doctor about what to do next. Reclast is a possibility for me also (I think).

REPLY
Please sign in or register to post a reply.