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PSA change from < .04 to < 0.1: Problem or no big deal?

Posted by johnny8924 @johnny8924, Mar 3 12:20pm

My last PSA result on November 4, 2025 was < .04. Today the result was < 0.1 Should I be concerned or is it no big deal? I'm 73 years old, Gleason 9 diagnosed August 2024, began Orgovyx August 2024, then 28 sessions of IMRT radiation, completed April 2025. Testosterone less than 1. Thank you for your thoughts, recommendations, etc!

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Jeff Marchi | @jeffmarc | Mar 9 6:37pm
In reply to @windrider354 "@jeffmarc Actually, the method information is relevant, but only if you are a clinical lab person...." + (show)
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@jeffmarc Actually, the method information is relevant, but only if you are a clinical lab person. They should have explained that the immunoassay is used for screening or following people who have not undergone therapy for PC. It is not ultrasensitive, as evidenced by the fact that numbers below 0.1 are not reported. This latest result is not informative and the test should be repeated with the order specifying the ultrasensitive (chemiluminescent) method.
Actually, Quest should have done this automatically since a previous result was done by this method.

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@windrider354
I did mean irrelevant to the normal public. There’s no meaning in those explanations that the average person can understand.

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