psa change

Are you getting tested every three months? You could get an MRI to see if there’s a noticeable metastasis inside your prostate PIRADS 4 or 5.

You could get a PSE test to see if there is any noticeable prostate cancer in your bloodstream. Some doctors use the decipher test for the same reason. Either test can decide whether or not you stay on active surveillance.

You could get another biopsy, but the above options could delay that.

If you're being tested frequently, see if the level stays higher on the next text. Sometimes PSA fluctuations are just temporary.

Then follow that a conversation with your oncology team. It might or might not matter, and as @jeffmarc mentioned, there are ways to narrow it down.

Best of luck!

How long have you been on active surveillance?

I had that situation during the 9 years that I was on active surveillance (PSA increased from 4.0 to 8.0).
Get as much more information as you can:
> Regular PSA tests, with:
> % Free PSA
> PSA Density
> PSA Doubling Time
> PSE Test

Also:
> Biomarker (genomic) test (with biopsied tissues)
> MRI (if data calls for it)

With all that information, you’ll have enough to figure out what’s next.

Did you do anything to cause a rise in PSA?

ok as paul harvey used to say now the rest of the story so they rec repeat in 6 weeks psa essentially the same altho 7.9 repeat 3 mos later now 9.3 mri eventually showed more prostate lesions and biopsy( now 6 mos later) gleason 7(4/3) with cribriform changes now intervention required had surg( robotic total with sem ves and nodes removed) altho psma neg path showed spread to one sem ves ie now p3tbno ie much higher risk bottom line is in my opinion( happen to be physician) ANY significant change needs to be aggressively evaluated and promptly thoughts?