PSA - 17.1, are Lupron injections necessary?

Posted by yuliyalt @yuliyalt, Apr 27, 2023

My grandfather is 79, his PSA level is 17.1, he is NOT on any treatment currently. He is generally healthy and is not taking ANY medication. Should he be doing Lupron injections or with this level PSA not yet? I read the side effects and not sure the benefits outweigh the risk, in his case…
If not Lupron, are there any other treatment he should be on to ensure his PSA is not climbing up?
- concerned granddaughter

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Don't get it it the loss of quality of life is not worth it.

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I think that ADT with lupron is necessary. I was on it and Erleada for 13 months. The meds had manageable side effects ( mostly fatigue and hot flashes ) but they did me a lot of good. My PSA is now .01 and the doctors monitor me every 3 months and my cancer is presently sleeping. If it wakes up I suspect that they will initially put me back on the same treatment. Lupron is part of my plan to have a quality of life for as long as possible. I am 76. Good luck !

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@hbp

I think that ADT with lupron is necessary. I was on it and Erleada for 13 months. The meds had manageable side effects ( mostly fatigue and hot flashes ) but they did me a lot of good. My PSA is now .01 and the doctors monitor me every 3 months and my cancer is presently sleeping. If it wakes up I suspect that they will initially put me back on the same treatment. Lupron is part of my plan to have a quality of life for as long as possible. I am 76. Good luck !

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78 on Xtandi and Ageva feel great and Zolodex injections

If it stops working then new drugs coming enoblituzumab phase 2 studies may be ready

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@hbp

I think that ADT with lupron is necessary. I was on it and Erleada for 13 months. The meds had manageable side effects ( mostly fatigue and hot flashes ) but they did me a lot of good. My PSA is now .01 and the doctors monitor me every 3 months and my cancer is presently sleeping. If it wakes up I suspect that they will initially put me back on the same treatment. Lupron is part of my plan to have a quality of life for as long as possible. I am 76. Good luck !

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Don't get them I got a 6 month shot and 15 months later my testosterones levels have not returned. I has ruined my quality of life.

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@gdimond

Don't get them I got a 6 month shot and 15 months later my testosterones levels have not returned. I has ruined my quality of life.

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A year after Lupron my testosterone was 150.

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with a PSA of 17, should not one get a biopsy? My PSA moved from 3 to 4...I received a biop & found localized cancer...ed

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@narus

A year after Lupron my testosterone was 150.

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mine is 42.

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My Gleason 9 CR PC is now sleeping, after RP and a year of lupron and Erleada. UCLA doctors told me if the cancer wakes up, they will probably put me back on lupron and Erleada and keep me there until it stops working or the side effects become too much. It seems to be that the strategy is to move me from one type of treatment to another after the cancer grows under the former treatment. ADT helped me and the fatigue and hot flashes were liveable.

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@gdimond

Don't get them I got a 6 month shot and 15 months later my testosterones levels have not returned. I has ruined my quality of life.

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Gdimond, Lupron also adversely affected me. My testosterone is about 15 or below and I feel exhausted all the time. In what way has your quality of life been impacted?

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@gdimond

Don't get them I got a 6 month shot and 15 months later my testosterones levels have not returned. I has ruined my quality of life.

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Narus, after taking Lupron my testosterone dropped to about 15 and has never been much above that. I stopped Lupron about 4 years ago. I feel exhausted all the time. In what way has your quality of life been impacted?

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