1. < Prostate Cancer

Proton Therapy Vs Prostate removal?

Posted by dude7707 @dude7707, Dec 23, 2024

68 single man, last PSA 3.99 when having prostate transpirneal biospy at Fred Hutch Cancer Center.....waiting for results right before Christmas! Last PSA before 12.20.24 - 4.55.
Q's: How can there be a current reading of PSA without FHCC taking my blood the normal method or does it matter?

I assume they obtained it through the biospy method?

Once I obtain the gleasons score, I assume depending how
aggresive the cancer is will depend which treatment to take
correct? Proton Vs removal of Prostate?

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

jc76 | @jc76 | 4 days ago
In reply to @dude7707 "Thank you JC, it appears the GC is 6, but then there is a statement stating..." + (show)
@dude7707

Thank you JC, it appears the GC is 6, but then there is a statement stating

COMMENT:
A-G) Examined biopsy cores show prominent changes of glandular hyperplasia with abundant intermixed high grade prostatic intraepithelial neoplasia (HGPIN). Some areas of HGPIN have adjacent small atypical glands. Performed HMWCK immunostains of multiple biopsy cores show preserved (at least partial to focal) basal cell staining in most small atypical glands. While these background changes made interpretation more challenging, definitive carcinoma is identified in Parts B, D, and F.

This doesn't look good IMO.

Jump to this post

@dude7707
If me would feel the same way about contradiction. Your pathology report has a lot of technical information that would be best explained to you by your urologist.

Not a medical professional and certainly would not try to diagnose or give you medical determinations, or treatment options that should come from your medical professionals including second opinions. If me I would asked our urologist to explain the pathlogy to you. .

Pathologists are the ones doing the pathology reports and what they are doing is comparing normal prostate cells with abnormal ones. It can be subjective and what one see another will disagree and that is where tests like Decipher are more specific.

The low Gleason Score of 6 is good. It is a determination of risks of the cancer. Wish mine had been 6. I was 3+4=7. But I can see your confusion and same confusion I would feel with the last sentence where states "definite carcinoma is identified in parts B,D, and F."

I would suggest going back to your urologist and have him or her explain the meaning of the pathology report and any questions you have. That will really help explain the report from a medical professional.

Pathology reports are very technical and thus your urologist should be explaining (both my urologist and my R/O explained mine) to you what they mean and any treatment options specific to you.

If me would be asking a lot of questions of urologist and get a good explanation of the diagnosis and pathology report. Then you will have a better clarification and any treatment options specific to you.
Good Luck!!!

REPLY
1 reply
dude7707 | @dude7707 | 3 days ago

Thanks for the information and your reply Jeff.

In reply to @dude7707 "Thank you JC, it appears the GC is 6, but then there is a statement stating..." + (show)
A Quick check of HGPIN Shows that it is just a possible sign that there could be cancer in the future. You could go on active surveillance with this. - That is EXACTLY what the urolgists recommended..... and check PSA in 6 months and follow up with biospy in 1 year.

The article about HGPIN Included this information which you may have already seen.
Certain medications, such as finasteride or dutasteride, may help to reduce the risk of developing prostate cancer.

REPLY
dude7707 | @dude7707 | 3 days ago
In reply to @jc76 "@dude7707 If me would feel the same way about contradiction. Your pathology report has a lot..." + (show)
@jc76

@dude7707
If me would feel the same way about contradiction. Your pathology report has a lot of technical information that would be best explained to you by your urologist.

Not a medical professional and certainly would not try to diagnose or give you medical determinations, or treatment options that should come from your medical professionals including second opinions. If me I would asked our urologist to explain the pathlogy to you. .

Pathologists are the ones doing the pathology reports and what they are doing is comparing normal prostate cells with abnormal ones. It can be subjective and what one see another will disagree and that is where tests like Decipher are more specific.

The low Gleason Score of 6 is good. It is a determination of risks of the cancer. Wish mine had been 6. I was 3+4=7. But I can see your confusion and same confusion I would feel with the last sentence where states "definite carcinoma is identified in parts B,D, and F."

I would suggest going back to your urologist and have him or her explain the meaning of the pathology report and any questions you have. That will really help explain the report from a medical professional.

Pathology reports are very technical and thus your urologist should be explaining (both my urologist and my R/O explained mine) to you what they mean and any treatment options specific to you.

If me would be asking a lot of questions of urologist and get a good explanation of the diagnosis and pathology report. Then you will have a better clarification and any treatment options specific to you.
Good Luck!!!

Jump to this post

I would suggest going back to your urologist and have him or her explain the meaning of the pathology report and any questions you have. That will really help explain the report from a medical professional. - Urolgists recommended, active suvelliance..... and check PSA in 6 months and follow up with biospy in 1 year.

REPLY
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