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Prostate metastasis to bones and liver: Doctor suggesting Keytruda

Posted by topsz @topsz, Oct 29, 2024

Any info for help on this? Two radiation trials lowered psa for awhile, now levels are soaring. Dr says no more radiation. Dr is suggesting Keytruda but I have read terrible things about drug. Any advise??

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heavyphil | @heavyphil | Mar 17 7:40am
In reply to @cooper1076 "In the same boat with same medical treatment: prostate removal, immediate PSA return. PSMA negative: salvage..." + (show)
@cooper1076

In the same boat with same medical treatment: prostate removal, immediate PSA return. PSMA negative: salvage radiation with six months of Lupron, PSA undetectable until Lupron stopped; rapid PSA to now 1.7, PSMA scan again negative. My two treating doctors are in disagreement: one of my doctors, and oncologist says I should go ahead with an Aximun scan because my cancer will continue not to show up under PSMA. My other doctor, a radiation oncologist disagrees and wants me to wait to have yet another PSMA Pet. Blue Shield refuses coverage for Aximun until my PSA reaches 2.2. Crazy to deal with this mentally…

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Yeah, sure is. I’m learning that PSMA is not all I’d hoped it was. The Axumin is sometimes better in some cases.
If you’re already at 1.7, perhaps waiting for 2.1 is not unreasonable. I mean, your PSA is rising and you’ll have to go on ADT again, but I don’t think that med would change by a .04 change in your PSA.
However, if an Axumin scan can pick up what a PSMA cannot, you might have a chance at eradicating it with SBRT and quit the ADT after resolution.
My Axumin scan cost me $7600 6 yrs ago and I have no idea what it costs now, but if insurance will cover it so much the better.

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