Prostate biopsy
When I had my biopsy in 2024 they found 8% of one core with 3+3 =6 apendocarcinoms and 2% of one core that was 3+4 =7 this year my mri was unchanged but my PSA went from 6 To 11 so they did another biopsy and I only had 2% of one core that was 3+3 =6 . I have not talked to my doc yet but what are the chances that that 2% of one core could have been reevaluated as a 6 instead of a 7? The biopsy was a in guided perineal biopsy excuse my spelling p.m.
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If you have 3+4 then you have PC. Most prostate specialists would tell you that Gleason 6 isn’t cancer, or at least cancer that poses any risk.
Psa density is a useful thing. Maybe I missed it, but what is the size in cc of your prostate? With size and psa then density can be calculated.
This should help. https://malecare.org/psa-velocity-and-psa-density-in-prostate-cancer-evaluation/
Large prostates can generate lots of psa. Also chronic prostatitis can cause the same thing. .