I am here to hopefully get some insight for my husband, who has been off work since the end of July due to a health issue we still can't figure out. We are considering taking the next step and having our primary care physician refer us to the Mayo Clinic. His symptoms: fatigue, pressure at base of skull/upper neck, off balance sensation (no spinning - just off balance), stress makes it worse, visual stimulation (people walking by, traffic) makes him feel worse, mood swings, can't think or get words out at times, feels mentally slow, can't concentrate, eyes water when he feels bad, ears feel like they are draining all the time, feels worse as the day goes on. He has had an MRI with contrast and CT scan and they came back normal. He has had inner ear testing and was ruled out (no inner ear issues supposedly), has done vesitbular rehabilitiation, has been on prednisone, Relefan (neurologist had theory he had some inflammation somewhere causing his brain to receive mixed signals but that didn't pan out). Our neurologist now thinks there is a disconnect between his equilibrium and his brain and has prescribed a new medication that is supposed to help his brain from being overstimulated. We are at a loss - we have a 22 month old that he can't roll around and play with on the floor and is on disability. He has no quality of life at the age of 39. If you have any experience in similar symptoms and have determined the issue, please share! We are at a loss!!