PPI use and side effects

Posted by bosco17 @bosco17, Nov 4, 2022

Ive been on 40mg of Pantoprzole for 4 weeks and my RBC count, Hemoglobin,Iron, Hematocrit have gone abnormal. Anyone else having these types problems?

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@bosco17

Anybody taking this medication and experiencing side effects: INSOMNIA, depression, joint pain, ANXIETY, tingling nerves, dry mouth, fatique, excessive urination, heart pressure or palpatations, scatchy throat, etc, etc,. This is a nightmare!! What side effects are you experiencing and how do you handle it?????

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I asked my Primary care Dr. about the drug Pantaprazole and it's side effects and he said would you rather have cancer or deal with side effects of the PPi? He said that doesn't mean that I'll get bad bones or kidney problems.

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@bosco17

Anybody taking this medication and experiencing side effects: INSOMNIA, depression, joint pain, ANXIETY, tingling nerves, dry mouth, fatique, excessive urination, heart pressure or palpatations, scatchy throat, etc, etc,. This is a nightmare!! What side effects are you experiencing and how do you handle it?????

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Tried 6 PPIs each one horrible side effects
Luckily mine were small Dr said he wasn’t worried wanted me to try to relax get excersise and enjoy life each day due gut therapy, Nerva tapes and laugh great advice just some days not enough and work with a FODMAP trained registered dietician

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@bosco17

Anybody taking this medication and experiencing side effects: INSOMNIA, depression, joint pain, ANXIETY, tingling nerves, dry mouth, fatique, excessive urination, heart pressure or palpatations, scatchy throat, etc, etc,. This is a nightmare!! What side effects are you experiencing and how do you handle it?????

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Hello there I started taking Pantroprazole 40mg twice a day since 12/10/2022 I haven't felt much of those side effects But I do feel anxiety and dry itchy patches of skin. My Anxiety might be because of the final diagnosis of my ulcer though. For me a week after finding out I had an ulcer, I was told that what they found after biopsies turned out to be cancer. The whole experience so far this past month has caused me major Anxiety. How long have you been taking this medication? Sorry if this scares/worries you in any ways.

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Hello; I have been on PPIs [Rabaprozole [20mgs 2x per day]] for over a year now and they work well for GERD with no side effects, YET. I know about the long term effects but they work for me. [H2 blockers don't] so I have little choice other than the surgery "Funduplication" which I would like to avoid. I Have tried Diet change to no avail.However for the last 2 weeks I have experienced a continuos chronic stomach ache, mild most of the time but is now becoming more intense. No other symptoms just general belly ache. From your experience has anyone else found this be a side effect of long term PPI use? or something else? Doc appt in a week. Thanks

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@billgil

Hello; I have been on PPIs [Rabaprozole [20mgs 2x per day]] for over a year now and they work well for GERD with no side effects, YET. I know about the long term effects but they work for me. [H2 blockers don't] so I have little choice other than the surgery "Funduplication" which I would like to avoid. I Have tried Diet change to no avail.However for the last 2 weeks I have experienced a continuos chronic stomach ache, mild most of the time but is now becoming more intense. No other symptoms just general belly ache. From your experience has anyone else found this be a side effect of long term PPI use? or something else? Doc appt in a week. Thanks

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I developed osteopinia after 24 years of PPI use. When on PPIs your body doesn't absorb calcium carbonate. You need calcium citrate. I was 10yrs into PPI use when I learned that little tidbit. Also, you will not absorb protein bound vitamin B12 because of the higher pH in the stomach created by PPIs. This will cause you to become deficient, so research problems caused by this. If this happens you can also lose tastebuds.
I had to remain on these medications after a Nissan Fundalplication because of 8 cm of Barrets Esophagus and still having mild gerds. I am assuming you have a Hiatal Hernia and that's why a Nissan Fundalplication was mentioned. If that's not the case perhaps your lower esophageal sphincter is not functioning properly. A LINX Band would fix that.
When I had my Nissan Fundalplication I was 34yrs old and most of my stomach was in my chest. At the age of 59 in 2019 I had a repeat Hiatal hernia repair with a LINX Band placement. At that point I was double dosed on 2 different meds for Gerds, worsening reflux and a lot of painful heartburn. My surgeon told me if I had waited another year my stomach would have been in my chest again. Now 4 yrs post op I have mild heartburn again and another small Hiatal Hernia. The hole in the diaphragm just keeps coming back. I've been off PPIs for 4 yrs now. Hopefully I'm the odd patient with reoccurring problems and you won't experience any like that. Whatever I learned about deficiencies I learned on my own. No Dr ever mentioned anything.! Research, research, research. Good luck, Sylvia

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@sylvias

I developed osteopinia after 24 years of PPI use. When on PPIs your body doesn't absorb calcium carbonate. You need calcium citrate. I was 10yrs into PPI use when I learned that little tidbit. Also, you will not absorb protein bound vitamin B12 because of the higher pH in the stomach created by PPIs. This will cause you to become deficient, so research problems caused by this. If this happens you can also lose tastebuds.
I had to remain on these medications after a Nissan Fundalplication because of 8 cm of Barrets Esophagus and still having mild gerds. I am assuming you have a Hiatal Hernia and that's why a Nissan Fundalplication was mentioned. If that's not the case perhaps your lower esophageal sphincter is not functioning properly. A LINX Band would fix that.
When I had my Nissan Fundalplication I was 34yrs old and most of my stomach was in my chest. At the age of 59 in 2019 I had a repeat Hiatal hernia repair with a LINX Band placement. At that point I was double dosed on 2 different meds for Gerds, worsening reflux and a lot of painful heartburn. My surgeon told me if I had waited another year my stomach would have been in my chest again. Now 4 yrs post op I have mild heartburn again and another small Hiatal Hernia. The hole in the diaphragm just keeps coming back. I've been off PPIs for 4 yrs now. Hopefully I'm the odd patient with reoccurring problems and you won't experience any like that. Whatever I learned about deficiencies I learned on my own. No Dr ever mentioned anything.! Research, research, research. Good luck, Sylvia

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I forgot to mention belly aches/ nausea are common with GERDS.

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@billgil

Hello; I have been on PPIs [Rabaprozole [20mgs 2x per day]] for over a year now and they work well for GERD with no side effects, YET. I know about the long term effects but they work for me. [H2 blockers don't] so I have little choice other than the surgery "Funduplication" which I would like to avoid. I Have tried Diet change to no avail.However for the last 2 weeks I have experienced a continuos chronic stomach ache, mild most of the time but is now becoming more intense. No other symptoms just general belly ache. From your experience has anyone else found this be a side effect of long term PPI use? or something else? Doc appt in a week. Thanks

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I hear so many reasons why ppi’s are bad to take long term. I think if you change your diet you have to be so good about all the things you shouldn’t eat and do it for a long enough time to see it work.

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@billgil

Hello; I have been on PPIs [Rabaprozole [20mgs 2x per day]] for over a year now and they work well for GERD with no side effects, YET. I know about the long term effects but they work for me. [H2 blockers don't] so I have little choice other than the surgery "Funduplication" which I would like to avoid. I Have tried Diet change to no avail.However for the last 2 weeks I have experienced a continuos chronic stomach ache, mild most of the time but is now becoming more intense. No other symptoms just general belly ache. From your experience has anyone else found this be a side effect of long term PPI use? or something else? Doc appt in a week. Thanks

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I would take my ppi 1/2 hr before supper, when do you take yours?

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@billgil

Hello; I have been on PPIs [Rabaprozole [20mgs 2x per day]] for over a year now and they work well for GERD with no side effects, YET. I know about the long term effects but they work for me. [H2 blockers don't] so I have little choice other than the surgery "Funduplication" which I would like to avoid. I Have tried Diet change to no avail.However for the last 2 weeks I have experienced a continuos chronic stomach ache, mild most of the time but is now becoming more intense. No other symptoms just general belly ache. From your experience has anyone else found this be a side effect of long term PPI use? or something else? Doc appt in a week. Thanks

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1/2 to 1 HR before lunch then Dinner [2x per day rabaprozole]. No meals after 7PM. All my issues are with sleeping at night. I can get through the day OK, so I take 2 PPIs more toward the evening. I am 75 yrs old so the Long term effects of PPis are not as important, Quality of life now is what I need, and no effects after 2 years so far.

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@billgil

Hello; I have been on PPIs [Rabaprozole [20mgs 2x per day]] for over a year now and they work well for GERD with no side effects, YET. I know about the long term effects but they work for me. [H2 blockers don't] so I have little choice other than the surgery "Funduplication" which I would like to avoid. I Have tried Diet change to no avail.However for the last 2 weeks I have experienced a continuos chronic stomach ache, mild most of the time but is now becoming more intense. No other symptoms just general belly ache. From your experience has anyone else found this be a side effect of long term PPI use? or something else? Doc appt in a week. Thanks

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I stop eating 3-5 pm everyday. I then drink only water.

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