PPI use and side effects

Posted by bosco17 @bosco17, Nov 4, 2022

Ive been on 40mg of Pantoprzole for 4 weeks and my RBC count, Hemoglobin,Iron, Hematocrit have gone abnormal. Anyone else having these types problems?

Interested in more discussions like this? Go to the Digestive Health Support Group.

I've been on it for 4 yrs. The only time mine was abnormal was when I had a bleeding ulcer.

REPLY

I think its possible but PA said it's rare. Have you had an endoscopy, colonoscopy and capsule endoscopy to rule out bleeding elsewhere? I had those done. Sometimes one may have iron malabsorption issues.

REPLY
@jackielb

I think its possible but PA said it's rare. Have you had an endoscopy, colonoscopy and capsule endoscopy to rule out bleeding elsewhere? I had those done. Sometimes one may have iron malabsorption issues.

Jump to this post

Everything was normal(in my CBC blood test) before starting 40mg of Pantoprozole. No abnormalties in RBC, Hemoglobin,& Hemoacrit on 10/10/22. 24 days after starting PPI(11/3/22) my CBC Blood test came back showing Anemia. Nothing changed in those 24 days except the start of PPI use!! I believe it has to do with absorbtion of iron due to the acid suppression from PPIs but Im going to follow up with a hematologist to make sure.

REPLY

Please let us know what hematologist says.

REPLY

I’m a double red blood donor and my iron is always good before donating.

REPLY

Anybody taking this medication and experiencing side effects: INSOMNIA, depression, joint pain, ANXIETY, tingling nerves, dry mouth, fatique, excessive urination, heart pressure or palpatations, scatchy throat, etc, etc,. This is a nightmare!! What side effects are you experiencing and how do you handle it?????

REPLY
@bosco17

Anybody taking this medication and experiencing side effects: INSOMNIA, depression, joint pain, ANXIETY, tingling nerves, dry mouth, fatique, excessive urination, heart pressure or palpatations, scatchy throat, etc, etc,. This is a nightmare!! What side effects are you experiencing and how do you handle it?????

Jump to this post

Somewhat. But side effects subside over time. I have been thinking of having nissen fundoplication or linx procedure for GERD and hiatal hernia.

REPLY
@bosco17

Anybody taking this medication and experiencing side effects: INSOMNIA, depression, joint pain, ANXIETY, tingling nerves, dry mouth, fatique, excessive urination, heart pressure or palpatations, scatchy throat, etc, etc,. This is a nightmare!! What side effects are you experiencing and how do you handle it?????

Jump to this post

I take 40mg 1/2 hr before supper and the only side effect I get is muscle cramps in my calf of the leg. I've been on it for about 5 years. I get scoped this year so I hope I have no issues.

REPLY
@jackielb

Somewhat. But side effects subside over time. I have been thinking of having nissen fundoplication or linx procedure for GERD and hiatal hernia.

Jump to this post

I have similar side effects, especially joint pain and tingling nerves ..but not dry mouth, tons of something…sticky saliva? Jackielb…..how long did symptoms take to subside?

REPLY
@bosco17

Anybody taking this medication and experiencing side effects: INSOMNIA, depression, joint pain, ANXIETY, tingling nerves, dry mouth, fatique, excessive urination, heart pressure or palpatations, scatchy throat, etc, etc,. This is a nightmare!! What side effects are you experiencing and how do you handle it?????

Jump to this post

I’m on 40mg pantaprozole for 9 months now and so far no issues.

REPLY
Please sign in or register to post a reply.