Post SBRT and ADT PSA Results

Posted by toolbelt @toolbelt, Oct 7 1:00pm

Quick update here, had labs today, see RO Wednesday.

At diagnosis about a year ago, 68 year old, PSA 7.4, one 4+3, one 3+3, Decipher 0.84, contained to prostate confirmed via PSMA PET.

SBRT concluded December 28, 2023 (36.25 Gy with boost to 40Gy at primary lesion).

Six months of Orgovyx concluded June 3, 2024.

PSA 3 months post SBRT and while still on ADT was 0.09.

PSA 6 months post SBRT, 1 month post ADT was 0.19.

PSA today, 9 months, 1 week post SBRT, 4 months post ADT 0.59.

RO referenced the 0.09 as the nadir at this point even though (in my mind) that may be an artificially low number due to the ADT.

While I am happy with the 0.59 today I had hoped it would have been lower. I am not all that concerned and I expect my RO will say that number is fine as it can take 12+months for the SBRT driven nadir (if you will) to be reached. I also expect he will suggest another PSA in 6 months.

If my RO says anything unexpected on Wednesday I will give you guys an update.

Stay Strong Brothers.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Colleen Young, Connect Director | @colleenyoung | Oct 15 7:28pm

@toolbelt, how are you doing? What did you learn from your radiation oncologist?

toolbelt | @toolbelt | Oct 15 9:17pm

In reply to @colleenyoung "@toolbelt, how are you doing? What did you learn from your radiation oncologist?" + (show)

Thanks Colleen. As my radiologist said " This is easy for me to say, but I am not at all concerned with your PSA. For SBRT, or for any trials I am doing, your numbers would not raise any flags. This could be a bounce, or a more realistic PSA number given the last two were still under the influence of ADT." Having said that, we will still consider the 0.09 as the nadir, unless it goes lower. Heading back in 3 months, and really not all that concerned at this point.