Pathology report is in 😮‍💨

Posted by topf @topf, Jun 20 11:28am

I was diagnosed with Gleason 4+4=8 in late December 2024. Had RARP on 06/16/25. PSMA was negative and Decipher 0.2. My last PSA was 5.5.

Pathology:
Negative surgical margins
Gleason 3+4=7
Stage T2c
No SVI
No LNI
Cancer involvement 11-20%
No adverse features such as Cribriform, IDC, or pattern 5.

Hugely relieved. Surprised by the downgrade from 4+4 to 3+4 (After Gleason 8 diagnosis I went into a mental tailspin of anxiety and depression).

Only fly in the ointment is that the stiches did not heal and that I will have to wear the catheter for another 10 days. 🤦

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survivor5280 | @survivor5280 | Jun 20 1:01pm

Congratulations on this wonderful news! The Cath is a bummer but easily offset by a downgrade and no negative info! 🥳

jayhall | @jayhall | Jun 20 1:28pm

Wonderful news! 🙂 Great news about the Path report Sorry about your stitches and the Cath. Thanks for the Update.

northoftheborder | @northoftheborder | Jun 20 1:56pm

3+4 is good news ("good" relatively speaking of course). Congrats!

surftohealth88 | @surftohealth88 | Jun 20 3:42pm

Great news about downgrading of gleason and no other adverse findings !!! : ))))
Best wishes for super fast and complete healing 🙂 !!!

topf | @topf | Jun 20 8:09pm

Thanks, everyone! 🙏
Good news, indeed.

bens1 | @bens1 | Jun 21 6:10am

Congratulations on your downgrade. 👍

perrychristopher | @perrychristopher | Jun 21 11:48am

Sounds like you had a great pathology report. Congratulations. Hoping you have a quick recovery from here on out.

vircet | @vircet | Jun 21 12:47pm

Congratulations! I am so happy for you.

brianjarvis | @brianjarvis | Jun 22 7:23am

Good news about downgrading.

As for pathology grade matching needle biopsy grade —> Though study results vary somewhat, studies between 2008 - 2023 indicate that initial grade and pathological grade match much of the time. This 2019 paper of a large study out of the UK indicated that initial biopsy and pathological grade matched 59% of the time; upgrades occurred 25% of the time; downgrades occurred 16% of the time: https://bmcurol.biomedcentral.com/articles/10.1186/s12894-019-0526-9

(I was diagnosed with 3+4 in 2020, so we scheduled proton radiation; a 2nd opinion upgraded the 3+4 to a 4+3, so we added 6-months of Eligard to the treatments that I had during April/May 2021.)

VancouverIslandHiker | @vancouverislandhiker | Jun 22 9:52am

TOPF - Nice pathology report with a down grade in Gleason IS solid good news . Any other symptoms fro you surgery ? What is your age and what was the PSA going into your surgery ? Stitches healed now - should be ... God Bless Sir . James on Vancouver Island .