Osteoporosis and Dental Work

Posted by skbd @skbd, Jul 31, 2025

I have completed 12 Evenity shots with No problems. I will begin Prolia at the end of August. I need a tooth extracted and have an appointment for August 8. The oral surgeon recommended doing it before starting Prolia. Has anyone had a tooth extracted and followed with an implant while on Prolia? I am not sure if I should have the implant.

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Profile picture for gowalking @gowalking

That is exactly how I hit the nightmare of osteoporosis.
I was told to go off of it before extraction/implant, which I did. I was due for my next dose of Prolia about 6 weeks after dental procedure. My doctor said it would be fine.
I had the tooth extracted and let that heal then the bone graft, let that heal and then the implant.
That whole process took about 8 weeks.
Once you stop Prolia, your bones deteriorate rapidly. PLEASE READ UP ON THAT.
After four weeks off Prolia, I had my first compression fracture. 5 more followed rapidly within weeks. Another two at one time followed by three more all at once.
The hospital had me checked by an Orthopeadic Spine Specialist who explained all this to me, telling me my bones were so soft, he was able to move them.
I've had two surgeries so far. He immediately sent me to their bone clinic where I am now treated by a doctor who specializes strictly in Osteoporsis. I am now on a treatment of Tymlos for two years. I have seven months to go and my bones show remarkable improvement. I've gone from osteoporosis to low bone mass in all measured areas. I am getting annual dexa scans to monitor progress. I'm not sure what I will be taking at the end of two years, but I will have to go on something.
PLEASE do read everything you can find about stopping treatment!!
I will try to find some information for you and will post it this evening.

Let me also mention the snowballing of other issues this has caused. I now have very thin jaw bones and need two implants but the doctor is not sure there will be enough bone to hold them. My face has sagged and I drool. The pain from the fractures was awful. I could not lay down. I slept in a chair. It was too painful to lift my legs to rest them on the ottoman. That led to blood pooling at my ankles, appointments with a vascular surgeon and ultimately vascular surgery. Now I have bulging veins and must wear ugly compression socks forever. I have a huge hump in my back which makes it impossible to lay flat, wear a bra that hooks in the back, sit in a wooden chair or look nice in blouses or tops, (baggy shirts are my new wardrobe). At the completion of my Tymlos treatment, we will begin to consider placing rods in my back to straighten it. I have lost 3" in height and gained a muffin top. I WAS 5'4" and 110# now I am 5'1". You would be amazed at the difference that is. I cannot reach in cabinets. All slacks and dresses have to be altered. I had a very tight, flat stomach. That 3" had to fall somewhere, so it fell right to my waist along with my boobs!
Ask your doctor if you can go off Prolia and on somethimg else before dental work.
I wish you the best and will be thinking of you. Just do your research, get a second or third opinion.

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What a road you have traveled. I am fortunate to be in this place, learning from the experiences you have gained. I thank you many times for sharing with us.

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Profile picture for 2reddogs @2reddogs

I had been on Prolia 5 years and needed a tooth extraction and a titanium implant. Long story, but my Rheumatologist gave the Periodontist the OK. Little or no warning from Rheumatologist and none from my Periodontist until a few minutes before he pulled the tooth regarding possible issues; I almost backed out of the procedure. My periodontist took several x-rays of my jaw/tooth over a 7 month period, checking for any issue pre and post extraction. He had me wait 7 months to complete the procedure and then another two weeks before having the crown.
I have since done my own research reading reputable scientific journals. It is recommended that you have the tooth pulled and implant procedure as close to the end of a Prolia injection (5.5-6 months post injection). There are additional issues for those with cancer that have had radiation so it is best to consult with a bone specialist or experienced oral surgeon. Ask all the questions you can, explain your worries share journals with them ask the what ifs….
Unfortunately my rheumatologists and periodontist were more concerned about jaw necrosis than the Prolia “holiday” I was on for 3 months post dental work. I am 71 and have never broken a bone in my body until I fractured my L-1 and L-3 not due to dental work but due to not getting back on Prolia within a shorter period. My rheumatologist never discussed the need to get right back on Prolia, even after she had me get an x-ray due to back pain 10 days before I fractured. I have since shared the research regarding Prolia and dental procedures and given it to my dentist, periodontist and rheumatologist. I am certain from my conversations w each they had little understanding of the side effects from Prolia when getting invasive dental work.
I have an appt. with an Endocronologist that specializes in bone health in February. I am hoping to find a way to relay off of Prolia. (She had a 12 month waitlist). Sadly knowledgable physicians are few and far between and these bone meds are fairly new and research is starting to get published. I hope my story empowers you in some way❤️

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I would be interested in learning any options recommended to get off Prolia. How long have you been taking Prolia? I’ve been on it for two years (4 injections).

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Profile picture for gently @gently

I think you should have the implant, I'm not sure you should take Prolia. The trouble with Prolia is that it prevents your bones from remodeling. Eventually your bones become avascular. So the bones are brittle because they haven't been renewed and then they become even more brittle. Many oral surgeons won't do surgery for patients on Prolia. Prolia weakens the immune system which makes you more susceptible to the ever-present germs in your mouth. Often we get antibiotics. But on Prolia there isn't the vascular system to take the antibiotic to a bone infection. All the bone can do is decay. There is a risk of osteonecrosis of the jaw with the use of Prolia.
Some never experience this and since you are just beginning Prolia, you might escape unharmed. But there is the risk of osteonecrosis with Evenity. So you might be set-up for harm. You might talk to you endocrinologist about pausing a month and starting Prolia at the end of September. It is safer if you've already had the root canal on that tooth. You probably know that once you start Prolia, it is difficult to stop the medication.

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@gently what about evenity. I am getting my 7th shot and need a tooth extracted and implant

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Profile picture for jessicamc @jessicamc

I had an extraction & implant before Prolia. I’ve had 4 Prolia injections and recently needed a root canal. The endodontist said he would send me to an oral surgeon, but an oral surgeon would refuse to treat me because of Prolia. The endodontist prescribed amoxicillin for ten days as a preventative measure. I started it two days before the root canal. He filled the interior of the tooth with calcium and added a temporary seal. I wait four weeks and return to see how it is working. Best case scenario I will need a new crown. If the tooth doesn’t look better, grind the tooth down to just below the gum line, seal off, and over time the body will absorb what is left of the tooth.
Implants are no longer an option due to Prolia. I regret going on it. I’m 79 and my mother had osteoporosis and refused to take Fosomax. She fell and broke several vertebrae. Her bones were so brittle drs couldn’t help her. She died 4 weeks after the fall. Watching her suffer made me want to try something, anything. Prolia is about as good as some other choices but dental issues create serious problems. I’m due for a 5th Prolia injection late September. I would like an alternative. Having a Dexa scan this month to see if two years of Prolia helped.

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@jessicamc follow-up one year later. My Dexa showed improvement, very happy with the scores. I will be 80 yrs Nov 2026! I had a consultation with a Mayo endocrinologist who cares for osteoporosis & osteopenia patients. She gave me 45 minutes of her precious time explaining options for treatment. I left feeling like Prolia for me at my age would be about as good as any. She said there are always new studies, new medicines coming available so keep abreast of new research. I expressed my concern about dental health and she said if a dentist won’t treat me, find a new dentist. There are new techniques, procedures for dental care being taught at good dental colleges. Fortunately, the endodontist that did a root canal last year is in that category.
One last note, I joined the local Y and am doing strength exercises. Working to prevent a fall and to hope I can keep bone density stable.

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Profile picture for msturcken @msturcken

@gently what about evenity. I am getting my 7th shot and need a tooth extracted and implant

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@msturcken, the risk of osteonecrosis of the jaw with Evenity is small much less than Prolia. You might consider that at 6 months you've gained the most bone that you will gain from the drug. It becomes more resorptive at 6 months. It is that resorptive process that makes osteonecrosis more likely. Some bone experts are prescribing Evenity for six months. Your specialist might agree to a transition to Forteo or Tymlos. Both are medications that have no risk of osteonecrosis, are even prescribed to treat osteonecrosis, and speed and strengthen the integration of bone to the implant.
Were you on antiresorptives bisphosphonates or Prolia in years prior to Evenity?
Is your implant surgeon aware of current and past medications. I keep hearing about oral surgeons who won't perform invasive procedures for patients on antiresorptive meds
But the one's I've seen are completely unaware of the possible impact.
The risk is cited at 0.03 to 0.05% with Evenity. I wish they'd do a study of the risk percentage among those who have had dental implants.

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Profile picture for jessicamc @jessicamc

@jessicamc follow-up one year later. My Dexa showed improvement, very happy with the scores. I will be 80 yrs Nov 2026! I had a consultation with a Mayo endocrinologist who cares for osteoporosis & osteopenia patients. She gave me 45 minutes of her precious time explaining options for treatment. I left feeling like Prolia for me at my age would be about as good as any. She said there are always new studies, new medicines coming available so keep abreast of new research. I expressed my concern about dental health and she said if a dentist won’t treat me, find a new dentist. There are new techniques, procedures for dental care being taught at good dental colleges. Fortunately, the endodontist that did a root canal last year is in that category.
One last note, I joined the local Y and am doing strength exercises. Working to prevent a fall and to hope I can keep bone density stable.

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@jessicamc
I don't know that the advice that if one dentist won't treat you, find another is very good advice. There is always a dentist somewhere who will do it for the money - good idea or not. I also have doubts about being treated at a dental school, if that is what your doctor has suggested. I took my son to the dental clinic at a local dental school - I have never seen such a disorganized, unsupervised amount of craziness - we went elsewhere for his dental surgery. I also have a good friend who is trying to get an implant done at the dental school (she is not on osteoporosis meds). She is being treated by the residents, who are full dentists and just expanding their skills or going into a specialty. It has been an awful experience - serious mistakes were made, and have to be fixed. Sounds like you are doing really well! I don't say these things to scare you, just to provide info to anyone it may help.

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Profile picture for lylii @lylii

@jessicamc
I don't know that the advice that if one dentist won't treat you, find another is very good advice. There is always a dentist somewhere who will do it for the money - good idea or not. I also have doubts about being treated at a dental school, if that is what your doctor has suggested. I took my son to the dental clinic at a local dental school - I have never seen such a disorganized, unsupervised amount of craziness - we went elsewhere for his dental surgery. I also have a good friend who is trying to get an implant done at the dental school (she is not on osteoporosis meds). She is being treated by the residents, who are full dentists and just expanding their skills or going into a specialty. It has been an awful experience - serious mistakes were made, and have to be fixed. Sounds like you are doing really well! I don't say these things to scare you, just to provide info to anyone it may help.

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@lylii no dental schools for me. I used to be on a hospital board that organized outreach clinics for people who had no healthcare resources. The endodontist I go to was trained at a highly rated medical college.

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