Newly diagnosed CLL How to interpret FISH results?

Posted by dhamra @dhamra, Jun 25 11:53pm

I just got back the FISH results and trying to understand what it means. "Results: abnormal."

"INTERPRETATION:
This analysis showed signal patterns consistent with trisomy 12 in
134/200 (67.0percent) cells scored.
The remaining probes showed normal results.
CLL with trisomy 12 is associated with an intermediate prognosis."

I guess, "intermediate prognosis" is moderately aggressive?
I have "numerous swollen lymph nodes."
I have had US biopsies, pet scan.

Still in shock. Family is so worried.

Interested in more discussions like this? Go to the Blood Cancers & Disorders Support Group.

Hi @dharma, You were recently diagnosed with CLL, which is a chronic and often slowly developing type of leukemia. I know it’s frighting to receive a new diagnosis. Even more frightening to read blood work and test results when you aren’t familar with any of the numbers or terminology. From my own experience, it’s better to wait and speak with your doctor than try to interpret results on your own. It’s normal for you and your family to be worried. If I can reassure you at all, CLL is one of the more treatable forms of leukemia.

I just responded to your other post about when you would have gotten CLL.
In that reply I’ve provided you with some good informational articles that will help familiarize you with CLL and the possible treatments. Here’s a link to that post: https://connect.mayoclinic.org/comment/1094363/

I think you’ll find those articles helpful. We also have quite a few members in our forum who have CLL. You can find all of the discussions by typing in CLL in the search box.
To get you started I think this would be a great conversation for you to pop into to meet other members. (The conversations are in chronological order so some are dated but still relevant. You can change the order from oldest to newest to see the most current discussion)
CLL. Newly Diagnosed:
https://connect.mayoclinic.org/discussion/cll-newly-diagnosed/

Have you had the consultation with your hematologist oncologist yet?

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Thanks for this info. I will check out your links. Thank you Lori.

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