Neuropathy and natural supplements such as magnesium and alpha acid

Posted by judyeccles @judyeccles, May 1 12:46pm

First off, I want to say if I didn’t have this Mayo Clinic website I would have lost it. Thank you for all the advise and caring you give.
Second, I would like to ask if anyone has had great results from taking alpha lipoid acid and magnesium ? I’m a soon to be a 67 year old female that neuropathy hit 3 years ago. It’s a nightmare at times. I have known people with Cancer that live normal lives now, which I’m very thankful for, it seems neuropathy just goes on, no matter. You can try to do the things you used to do but sometimes it is to no avail as it’s hard to even get out of bed in the morning because of pain. I also have the pchological problem of being so reliant on my husband when I have been independent , worked out, loved to cook, now it’s hard to stand, only short periods of time. I think I am over Dr.s, it’s like chasing the wind.
My question is, has anyone tried the alpha lopic acid along with magnesium ? How many milligrams is safe for a medium size woman and what is the best brand for both of these. Dr.s will poo poo this as they want to push the drugs, I’ve been prescribed everything and couldn’t tolerate Cymbalta, I almost scratched myself to the bone. I have been on steroids several times, it can destroy every part of your body, not sure why that is not realized. I want to finally try something natural, if anyone can help I would appreciate it very much.
Thank you, Judy

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Profile picture for mistyisle44 @mistyisle44

I would think that it shouldn't if you take them at quite separate intervals, especially up to two hours apart.

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Not very good advice

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Yes, there is something natural. It is called exercise! And I’m not trying to be funny. If you’re scratching yourself till you bleed, then it’s probably coming from your spine. At least that’s what happened to me. The itchiness eventually turned into numbness when the nerve endings were crushed as my vertebrae‘s grafted together, crushing the nerves in between when the disc fell out. The lumbar surgery put space in between my vertebrae for the nerves to grow back, but it’s been six years and the pain down my legs was excruciating. The Cortizone was amazing. Got rid of all the pain, but it’s not sustainable. I was so angry and disappointed and scared. I threw myself into exercise. Good breathing, walking and riding a stationary bike for a month every day got rid of the pain allowed me to sleep at night and improved all my blood labs and put me on a great path. All women after 50 should be taking vitamin D at least and you should be eating a good diet but then if you don’t take a good multivitamins and consult with your doctor. We are all individuals and so we all have deficiencies in someway or another. We have to work with a good natural path or Dr. to realize what our body doesn’t metabolize properly and take supplements for that. Without actually testing what’s in your bloodstream or at a cellular level “buyer beware“ You’re just getting scammed. It’s a process and it’s a job. There is no magical fix. There is no pill surgery or exercise alone that fixes it. If you are retired or a retirement age, geriatric aging is a given and it is your new job to figure out your body and sustain it. Good luck!

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Profile picture for John, Volunteer Mentor @johnbishop

Hi Judy @judyeccles, Sorry you haven't found anything that really helps. There are quite a few different discussions on supplements for neuropathy if you want to scan through the list here - https://connect.mayoclinic.org/search/discussions/?search=neuropathy%20supplements.

I don't have the pain that you have but do have the numbness that I've been dealing with for over 40 years. I didn't bother to get a diagnosis until 2016 and when I did I got the same answer from my Mayo neurologist after being diagnosed with idiopathic small fiber peripheral neuropathy - there aren't any medications that can help with the numbness. That got me looking into supplements and although it's not a cure I do believe it's helped reduce and possibly stopped the progression of my numbness symptoms. I shared my journey in another discussion here - https://connect.mayoclinic.org/comment/310341/.

The Foundation for Peripheral Neuropathy has a list of supplements shown to help folks with neuropathy at the end of their complementary and alternative therapies document here - https://www.foundationforpn.org/wp-content/uploads/2024/11/Complementary-and-Alternative-Treatments.pdf. They don't really say what the therapeutic dose for each are but I take most of them with the protocol that I have used since 2016. Here's a document put together by group that I order mine from but some you may be able to purchase the supplements elsewhere. I would just make sure the quality is good and is R-ALA for the alpha lipoic acid. I would also check with my doctor before starting the supplements.

Hope this helps.

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@johnbishop I just looked The Protocol pdf and was floored by the prices they charge!

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Profile picture for mikead63 @mikead63

@johnbishop I just looked The Protocol pdf and was floored by the prices they charge!

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Last time I priced it out it amounted to about a little over $6 a day. I like that it has all of the recommended supplements for providing the nerve’s a chance at healing/recovery. I used to purchase each of the supplements individually and each had different quantities in the bottle so they didn’t all run out at once. Made it a little more difficult to keep track of when to order. And I was paying more.

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Profile picture for bgator @bgator

Not very good advice

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Judy. My husband takes nervive ...has B12 and alpha lipoic in it. It seems to have worked for him. Pat Mohns

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Hello,
Like with anything for neuropathy, it's hit or miss. We try things and see if they may or may not work. However, it's really important to have a good neurologist and ask her or him prior to trying anything since the issue of side effects of anything we try is a complete mystery that depends totally on the respective complete state of our body. Different people experience different things.
Take care and have a serene day,
gus

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Profile picture for gus0557 @gus0557

Hello,
Like with anything for neuropathy, it's hit or miss. We try things and see if they may or may not work. However, it's really important to have a good neurologist and ask her or him prior to trying anything since the issue of side effects of anything we try is a complete mystery that depends totally on the respective complete state of our body. Different people experience different things.
Take care and have a serene day,
gus

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I agree with you entirely. People experience different things with meds--the recent COVID vaccine is one example. Good luck seeing a neurologist in any timely way. I am going to try physical therapy and see what if anything will help. It sure is frustrating.

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My MD prescribed Alpha-Lipoic acid pills about 6 or 8 weeks ago. I can't say that I've noticed any change. But no problems/side effects either.

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Profile picture for zoolook85 @zoolook85

My MD prescribed Alpha-Lipoic acid pills about 6 or 8 weeks ago. I can't say that I've noticed any change. But no problems/side effects either.

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How much are you taking, maybe you need a higher dose. I've been taking 1200mg a day for a few months, and it seems to be helping me.

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I'm taking 1200 also. I'm not giving up on it yet. My neuropathy was the result of injury. so it's not related to diabetes or autoimmune or whatever so not sure if that makes a difference. Anyway, I'll keep at it for a good while yet.

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