Zoledronic Acid: I need feed back for this drug please

I felt awful after the first infusion - flu like symptoms for over a week and at the 2 week mark I was still having really bad night sweats. I read somewhere that the rate of infusion could make a difference, so for the second infusion I asked the nurses if they could slow it down a little, which they did (from about 20 mins to almost 40 mins). I had zero problems that time and with subsequent infusions. So whether it was my body adjusting to the medicine or the rate of infusion, it got much better after round 1. Good luck and feel better.

I have heard that hydrating really well 24 hours before and after, slower infusion and premedicating (Tylenol or NSAID? Benadryl?) help. I have this in my future so thanks for the comment on the slower infusion.

carla702
I had problems where I nearly passed out during infusion so the following ones they slowed the infusion down and that helped. As far as the bone aches and feeling like a bad flu, that's part of it for some of us. If you can schedule toward the end of the week so you'll have a weekend to recuperate, it may help. I would tell my family when this was being done and they would know I'd just kind of be laying around for a while. The first time took me a week to recoup and after that a shorter period, maybe 3-4 days.

I had my first Zometa infusion for bone strengthening (along with my chemo treatment) due to bone metastasis. I felt like crap for 2-3 days, extreme fatigue, queasiness/loss of appetite, bone & muscle aches, headache. Much worse than chemo side effects. I’m scheduled for a second infusion in 3 weeks, and almost want to refuse it. I know the benefits likely outweigh the risks, but I’m also hesitant to do anything that further deteriorates my quality of life.
I think my oncologist said side effects may be less with second treatment. Anyone who can comment on your experience?

Thanks!!

@live
Actually, may I suggest that you should probably see dentist before and have all dental work that needs to be done first and then be cleared by dentist PRIOR to Zometa infusion as it could make things heal slower. Check with your oncologist and dentist prior.

Thanks for the info....Doctor also said be cautious with dental works after the infusion.

After treatment I usually slept most of the day. For the next couple of days I felt like I had the flu. I had two treatments three months a part. Sameness feeling both times.

Hi @live, I'd like to add my welcome. You'll notice that I moved your message to this existing discussion about Zometa (zoledronic acid). Click VIEW & REPLY to see past posts from fellow members like @roch @mbear @trixie1313 @kathysway who have had infusions with the bisphosphonate.

When will you start with treatment? What questions might you like to ask?

Does anyone has Zometa infusion? My doctor just recommend that to me.
I'd like to do some research and learn more on this drug.
Thanks.